Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HSD11B1	HGNC:5208 (HGNC) 3290 (Entrez Gene) 600713 (OMIM) HSD11B1 (Alliance of Genome Resources)	Chr1 q32.2	Chr1:209686178-209734949 (+) GRCh38	cortisone reductase deficiency cortisone reductase deficiency 2 essential hypertension hypertension pre-eclampsia type 2 diabetes mellitus	P28845 (UniProt | EBI) NM_181755 (RefSeq)
mouse	Hsd11b1	MGI:103562 (MGI) 15483 (Entrez Gene) Gene Tree Hsd11b1 (Alliance of Genome Resources)	Chr1 97.67 cM	Chr1:192903948-192946353 (-) GRCm39	cortisone reductase deficiency 2	15483 (NCBI Gene Model) P50172 (UniProt | EBI) NM_001420225 (RefSeq)
rat	Hsd11b1	RGD:2834 (Rat Genome Database) 25116 (Entrez Gene) Hsd11b1 (Alliance of Genome Resources)	Chr13 q27			P16232 (UniProt | EBI) NM_017080 (RefSeq)
zebrafish	hsd11b1la	ZDB-GENE-040426-1002 (Zebrafish Model Organism Database) 393293 (Entrez Gene) hsd11b1la (Alliance of Genome Resources)	Chr22			Q6PUF3 (UniProt | EBI) NM_200323 (RefSeq)
	hsd11b1lb	ZDB-GENE-101130-4 (Zebrafish Model Organism Database) 100333777 (Entrez Gene) hsd11b1lb (Alliance of Genome Resources)	Chr2			XP_009297199 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.