Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	YWHAE	HGNC:12851 (HGNC) 7531 (Entrez Gene) 605066 (OMIM) YWHAE (Alliance of Genome Resources)	Chr17 p13.3	Chr17:1344275-1400222 (-) GRCh38		P62258 (UniProt | EBI) NM_006761 (RefSeq)
mouse	Ywhae	MGI:894689 (MGI) 22627 (Entrez Gene) Gene Tree Ywhae (Alliance of Genome Resources)	Chr11 45.92 cM	Chr11:75623695-75656671 (+) GRCm39	left ventricular noncompaction Miller-Dieker lissencephaly syndrome	ENSMUSG00000020849 (Ensembl Gene Model) ENSMUSP00000070993 (Ensembl) ENSMUST00000067664 (Ensembl)
rat	Ywhae	RGD:62000 (Rat Genome Database) 29753 (Entrez Gene) Ywhae (Alliance of Genome Resources)	Chr10 q24			P62260 (UniProt | EBI) NM_031603 (RefSeq)
zebrafish	ywhae1	ZDB-GENE-030131-779 (Zebrafish Model Organism Database) 322060 (Entrez Gene) ywhae1 (Alliance of Genome Resources)	Chr15			NP_997770 (RefSeq) NM_212605 (RefSeq)
	ywhae2	ZDB-GENE-050306-44 (Zebrafish Model Organism Database) 503763 (Entrez Gene) ywhae2 (Alliance of Genome Resources)	Chr7			NP_001013359 (RefSeq) NM_001013341 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.