Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CIC	HGNC:14214 (HGNC) 23152 (Entrez Gene) 612082 (OMIM) CIC (Alliance of Genome Resources)	Chr19 q13.2	Chr19:42268530-42295797 (+) GRCh38	autosomal dominant intellectual developmental disorder 45	Q96RK0 (UniProt | EBI) NM_001386298 (RefSeq)
mouse	Cic	MGI:1918972 (MGI) 71722 (Entrez Gene) Gene Tree Cic (Alliance of Genome Resources)	Chr7 13.73 cM	Chr7:24967129-24993584 (+) GRCm39	disease of mental health	ENSMUSG00000005442 (Ensembl Gene Model) ENSMUSP00000132351 (Ensembl) ENSMUST00000169266 (Ensembl)
rat	Cic	RGD:1310706 (Rat Genome Database) 308435 (Entrez Gene) Cic (Alliance of Genome Resources)	Chr1 q21			NP_001100960 (RefSeq) NM_001107490 (RefSeq)
zebrafish	cica	ZDB-GENE-060503-700 (Zebrafish Model Organism Database) 560266 (Entrez Gene) cica (Alliance of Genome Resources)	Chr19			XP_009292279 (RefSeq)
	cicb	ZDB-GENE-030131-1966 (Zebrafish Model Organism Database) 323246 (Entrez Gene) cicb (Alliance of Genome Resources)	Chr16			XP_005173569 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.