Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PRRX1	HGNC:9142 (HGNC) 5396 (Entrez Gene) 167420 (OMIM) PRRX1 (Alliance of Genome Resources)	Chr1 q24.2	Chr1:170662728-170739421 (+) GRCh38	agnathia-otocephaly complex	P54821 (UniProt | EBI) NM_022716 (RefSeq)
mouse	Prrx1	MGI:97712 (MGI) 18933 (Entrez Gene) Gene Tree Prrx1 (Alliance of Genome Resources)	Chr1 70.53 cM	Chr1:163072688-163141279 (-) GRCm39		ENSMUSG00000026586 (Ensembl Gene Model) ENSMUSP00000027878 (Ensembl) ENSMUST00000027878 (Ensembl)
rat	Prrx1	RGD:628884 (Rat Genome Database) 266813 (Entrez Gene) Prrx1 (Alliance of Genome Resources)	Chr13 q22			P63014 (UniProt | EBI) NM_153821 (RefSeq)
zebrafish	prrx1a	ZDB-GENE-020905-5 (Zebrafish Model Organism Database) 406431 (Entrez Gene) prrx1a (Alliance of Genome Resources)	Chr2			NP_999899 (RefSeq) NM_214734 (RefSeq)
	prrx1b	ZDB-GENE-030131-9033 (Zebrafish Model Organism Database) 337089 (Entrez Gene) prrx1b (Alliance of Genome Resources)	Chr20			NP_956344 (RefSeq) NM_200050 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.