Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CRX	HGNC:2383 (HGNC) 1406 (Entrez Gene) 602225 (OMIM) CRX (Alliance of Genome Resources)	Chr19 q13.33	Chr19:47819779-47843330 (+) GRCh38	cone-rod dystrophy 2 Leber congenital amaurosis 7	O43186 (UniProt | EBI) NM_000554 (RefSeq)
mouse	Crx	MGI:1194883 (MGI) 12951 (Entrez Gene) Gene Tree Crx (Alliance of Genome Resources)	Chr7 8.6 cM	Chr7:15599872-15613880 (-) GRCm39	cone-rod dystrophy 2 Leber congenital amaurosis 7	12951 (NCBI Gene Model) O54751 (UniProt | EBI) NM_007770 (RefSeq)
rat	Crx	RGD:620511 (Rat Genome Database) 60446 (Entrez Gene) Crx (Alliance of Genome Resources)	Chr1 q21			NP_068627 (RefSeq) NM_021855 (RefSeq)
zebrafish	crx	ZDB-GENE-010403-1 (Zebrafish Model Organism Database) 81881 (Entrez Gene) crx (Alliance of Genome Resources)	Chr5			NP_694419 (RefSeq) NM_152940 (RefSeq)
	otx5	ZDB-GENE-030508-1 (Zebrafish Model Organism Database) 353179 (Entrez Gene) otx5 (Alliance of Genome Resources)	Chr15			NP_851848 (RefSeq) NM_181331 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.