Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZFYVE16
  • Mouse genes Zfyve16
  • Rat genes Zfyve16
  • Zfish genes zfyve16
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zfyve16

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005545	1-phosphatidylinositol binding	ZFYVE16	IDA		Human	PMID:11546807
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	ZFYVE16	IDA		Human	PMID:11433298
Molecular Function	GO:0005515	protein binding	ZFYVE16	IPI	UniProtKB:O60784	Human	PMID:14613930
Molecular Function	GO:0005515	protein binding	ZFYVE16	IPI	UniProtKB:Q15075	Human	PMID:14613930
Molecular Function	GO:0005515	protein binding	ZFYVE16	IPI	UniProtKB:O60784	Human	PMID:15657082
Molecular Function	GO:0005515	protein binding	ZFYVE16	IPI	UniProtKB:Q15075	Human	PMID:29568061
Cellular Component	GO:0005829	cytosol	ZFYVE16	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005769	early endosome	ZFYVE16	IDA		Human	PMID:11546807
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ZFYVE16	IDA		Human	GO_REF:0000052
Biological Process	GO:0016197	endosomal transport	ZFYVE16	IMP		Human	PMID:11546807
Biological Process	GO:0006622	protein targeting to lysosome	ZFYVE16	IMP		Human	PMID:11546807

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern