Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZC3H8
  • Mouse genes Zc3h8
  • Rat genes Zc3h8
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zc3h8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Zc3h8	IDA		Mouse	MGI:MGI:3777198|PMID:12077251
Molecular Function	GO:0005515	protein binding	ZC3H8	IPI	UniProtKB:Q9Y2F5	Human	PMID:23932780
Molecular Function	GO:0003723	RNA binding	ZC3H8	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	ZC3H8	HDA		Human	PMID:22681889
Molecular Function	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	Zc3h8	IDA		Mouse	MGI:MGI:3777198|PMID:12077251
Cellular Component	GO:0015030	Cajal body	ZC3H8	IDA		Human	PMID:23932780
Cellular Component	GO:0000791	euchromatin	ZC3H8	IDA		Human	PMID:23932780
Cellular Component	GO:0035363	histone locus body	ZC3H8	IDA		Human	PMID:23932780
Cellular Component	GO:0016604	nuclear body	ZC3H8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ZC3H8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Zc3h8	IDA		Mouse	PMID:11318609
Cellular Component	GO:0008023	transcription elongation factor complex	ZC3H8	IDA		Human	PMID:23932780
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ZC3H8	IDA		Human	PMID:12077251
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Zc3h8	IMP		Mouse	MGI:MGI:3777198|PMID:12077251
Biological Process	GO:0033085	negative regulation of T cell differentiation in thymus	ZC3H8	IMP		Human	PMID:12153508
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Zc3h8	IDA		Mouse	MGI:MGI:3777198|PMID:12077251
Biological Process	GO:0070245	positive regulation of thymocyte apoptotic process	ZC3H8	IMP		Human	PMID:12153508
Biological Process	GO:0045945	positive regulation of transcription by RNA polymerase III	ZC3H8	IMP		Human	PMID:23932780
Biological Process	GO:0046677	response to antibiotic	ZC3H8	IDA		Human	PMID:12153508
Biological Process	GO:0042795	snRNA transcription by RNA polymerase II	ZC3H8	IMP		Human	PMID:23932780
Biological Process	GO:0042796	snRNA transcription by RNA polymerase III	ZC3H8	IMP		Human	PMID:23932780
Biological Process	GO:0043029	T cell homeostasis	ZC3H8	IMP		Human	PMID:12153508

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern