Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WWC2
  • Mouse genes Wwc2
  • Rat genes Wwc2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wwc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019900	kinase binding	WWC2	IPI	UniProtKB:P41743	Human	PMID:24682284
Molecular Function	GO:0019900	kinase binding	WWC2	IPI	UniProtKB:Q9NRM7	Human	PMID:24682284
Molecular Function	GO:0060090	molecular adaptor activity	WWC2	IDA		Human	PMID:24682284
Cellular Component	GO:0005829	cytosol	WWC2	IDA		Human	PMID:24682284
Biological Process	GO:0035331	negative regulation of hippo signaling	WWC2	IDA		Human	PMID:24682284
Biological Process	GO:0046621	negative regulation of organ growth	WWC2	IMP		Human	PMID:24682284
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	WWC2	IDA		Human	PMID:24682284

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern