Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WDR6
  • Mouse genes Wdr6
  • Rat genes Wdr6
  • Zfish genes wdr6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wdr6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043560	insulin receptor substrate binding	Wdr6	IPI	RGD:1562442	Rat	PMID:17720279|RGD:2301084
Molecular Function	GO:0005515	protein binding	WDR6	IPI	UniProtKB:Q15831	Human	PMID:17216128
Molecular Function	GO:0005515	protein binding	WDR6	IPI	UniProtKB:P26045	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WDR6	IPI	UniProtKB:P26045	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WDR6	IPI	UniProtKB:Q9Y3R0-3	Human	PMID:32296183
Molecular Function	GO:0003723	RNA binding	WDR6	HDA		Human	PMID:22658674
Cellular Component	GO:0005737	cytoplasm	WDR6	IDA		Human	PMID:17216128
Cellular Component	GO:0005829	cytosol	WDR6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	WDR6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032991	protein-containing complex	Wdr6	IDA		Rat	PMID:17720279|RGD:2301084
Biological Process	GO:0070314	G1 to G0 transition	WDR6	IPI	UniProtKB:Q15831	Human	PMID:17216128
Biological Process	GO:0010507	negative regulation of autophagy	WDR6	IMP		Human	PMID:22354037
Biological Process	GO:0008285	negative regulation of cell population proliferation	WDR6	IDA		Human	PMID:17216128

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern