Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WDR59
  • Mouse genes Wdr59
  • Rat genes Wdr59
  • Zfish genes wdr59
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wdr59

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	WDR59	IPI	UniProtKB:Q96S15	Human	PMID:25263562
Molecular Function	GO:0005515	protein binding	WDR59	IPI	UniProtKB:A6NHX0	Human	PMID:26972053
Molecular Function	GO:0005515	protein binding	WDR59	IPI	UniProtKB:P58004	Human	PMID:26972053
Molecular Function	GO:0005515	protein binding	WDR59	IPI	UniProtKB:Q96S15	Human	PMID:28199315
Cellular Component	GO:0005829	cytosol	WDR59	IDA		Human	GO_REF:0000052
Cellular Component	GO:0061700	GATOR2 complex	WDR59	IDA		Human	PMID:23723238
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	WDR59	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005765	lysosomal membrane	WDR59	IDA		Human	PMID:28199306
Biological Process	GO:0034198	cellular response to amino acid starvation	WDR59	IMP		Human	PMID:23723238
Biological Process	GO:0032008	positive regulation of TOR signaling	WDR59	IMP		Human	PMID:23723238

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern