Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UGT1A10,UGT1A7,UGT1A8,UGT1A9
  • Mouse genes Ugt1a8
  • Rat genes Ugt1a8
  • Zfish genes ugt1a7,ugt1ab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ugt1a8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	UGT1A9	IPI	UniProtKB:P22309	Human	PMID:17179145
Molecular Function	GO:0019899	enzyme binding	UGT1A7	IPI	UniProtKB:P22309	Human	PMID:17179145
Molecular Function	GO:0019899	enzyme binding	UGT1A10	IPI	UniProtKB:P22309	Human	PMID:17179145
Molecular Function	GO:0019899	enzyme binding	UGT1A8	IPI	UniProtKB:P22309	Human	PMID:17179145
Molecular Function	GO:0004857	enzyme inhibitor activity	UGT1A7	IDA		Human	PMID:19996319
Molecular Function	GO:0004857	enzyme inhibitor activity	UGT1A8	IDA		Human	PMID:19996319
Molecular Function	GO:0005504	fatty acid binding	UGT1A8	IDA		Human	PMID:19996319
Molecular Function	GO:0015020	glucuronosyltransferase activity	UGT1A9	IDA		Human	PMID:18052087
Molecular Function	GO:0015020	glucuronosyltransferase activity	UGT1A9	IDA		Human	PMID:20056724
Molecular Function	GO:0015020	glucuronosyltransferase activity	UGT1A9	IDA		Human	PMID:20308471
Molecular Function	GO:0015020	glucuronosyltransferase activity	UGT1A9	IDA		Human	PMID:22579593
Molecular Function	GO:0015020	glucuronosyltransferase activity	UGT1A7	IDA		Human	PMID:17179145
Molecular Function	GO:0015020	glucuronosyltransferase activity	UGT1A7	IDA		Human	PMID:18052087
Molecular Function	GO:0015020	glucuronosyltransferase activity	UGT1A7	IDA		Human	PMID:18719240
Molecular Function	GO:0015020	glucuronosyltransferase activity	UGT1A7	IDA		Human	PMID:19996319
Molecular Function	GO:0015020	glucuronosyltransferase activity	UGT1A7	IDA		Human	PMID:20056724
Molecular Function	GO:0015020	glucuronosyltransferase activity	UGT1A7	IDA		Human	PMID:20308471
Molecular Function	GO:0015020	glucuronosyltransferase activity	UGT1A10	IDA		Human	PMID:18052087
Molecular Function	GO:0015020	glucuronosyltransferase activity	UGT1A10	IDA		Human	PMID:20056724
Molecular Function	GO:0015020	glucuronosyltransferase activity	UGT1A8	IDA		Human	PMID:18052087
Molecular Function	GO:0015020	glucuronosyltransferase activity	UGT1A8	IDA		Human	PMID:19996319
Molecular Function	GO:0015020	glucuronosyltransferase activity	UGT1A8	IDA		Human	PMID:20056724
Molecular Function	GO:0015020	glucuronosyltransferase activity	UGT1A8	IDA		Human	PMID:20308471
Molecular Function	GO:0015020	glucuronosyltransferase activity	Ugt1a8	IDA		Rat	PMID:15502008|RGD:2317077
Molecular Function	GO:0015020	glucuronosyltransferase activity	ugt1ab	IDA		Zfish	PMID:24728488
Molecular Function	GO:0015020	glucuronosyltransferase activity	ugt1a7	IDA		Zfish	PMID:24728488
Molecular Function	GO:0042803	protein homodimerization activity	UGT1A9	IDA		Human	PMID:17179145
Molecular Function	GO:0042803	protein homodimerization activity	UGT1A7	IDA		Human	PMID:17179145
Molecular Function	GO:0042803	protein homodimerization activity	UGT1A10	IDA		Human	PMID:17179145
Molecular Function	GO:0042803	protein homodimerization activity	UGT1A8	IDA		Human	PMID:17179145
Molecular Function	GO:0005080	protein kinase C binding	UGT1A7	IDA		Human	PMID:18556656
Molecular Function	GO:0005080	protein kinase C binding	UGT1A10	IDA		Human	PMID:18556656
Molecular Function	GO:0001972	retinoic acid binding	UGT1A9	IDA		Human	PMID:20308471
Molecular Function	GO:0001972	retinoic acid binding	UGT1A7	IDA		Human	PMID:20308471
Molecular Function	GO:0005496	steroid binding	UGT1A8	IDA		Human	PMID:19996319
Cellular Component	GO:0005783	endoplasmic reticulum	UGT1A9	IDA		Human	PMID:17179145
Cellular Component	GO:0005783	endoplasmic reticulum	UGT1A7	IDA		Human	PMID:17179145
Cellular Component	GO:0005783	endoplasmic reticulum	UGT1A7	IDA		Human	PMID:18556656
Cellular Component	GO:0005783	endoplasmic reticulum	UGT1A10	IDA		Human	PMID:17179145
Cellular Component	GO:0005783	endoplasmic reticulum	UGT1A10	IDA		Human	PMID:18556656
Cellular Component	GO:0005783	endoplasmic reticulum	UGT1A8	IDA		Human	PMID:17179145
Cellular Component	GO:0016020	membrane	Ugt1a8	IDA		Rat	PMID:15502008|RGD:2317077
Biological Process	GO:0052695	cellular glucuronidation	UGT1A9	IDA		Human	PMID:22579593
Biological Process	GO:0052695	cellular glucuronidation	UGT1A7	IDA		Human	PMID:17179145
Biological Process	GO:0052695	cellular glucuronidation	UGT1A7	IDA		Human	PMID:18719240
Biological Process	GO:0052695	cellular glucuronidation	UGT1A10	IDA		Human	PMID:20056724
Biological Process	GO:0071407	cellular response to organic cyclic compound	Ugt1a8	IEP		Rat	PMID:11992647|RGD:2317078
Biological Process	GO:0046226	coumarin catabolic process	Ugt1a8	IDA		Rat	PMID:15502008|RGD:2317077
Biological Process	GO:0008210	estrogen metabolic process	UGT1A7	IDA		Human	PMID:18719240
Biological Process	GO:0051552	flavone metabolic process	UGT1A9	IDA		Human	PMID:18052087
Biological Process	GO:0051552	flavone metabolic process	UGT1A10	IDA		Human	PMID:18052087
Biological Process	GO:0051552	flavone metabolic process	UGT1A8	IDA		Human	PMID:18052087
Biological Process	GO:0052696	flavonoid glucuronidation	UGT1A9	IDA		Human	PMID:20056724
Biological Process	GO:0052696	flavonoid glucuronidation	UGT1A7	IDA		Human	PMID:20056724
Biological Process	GO:0052696	flavonoid glucuronidation	UGT1A8	IDA		Human	PMID:20056724
Biological Process	GO:0008202	steroid metabolic process	UGT1A8	IDA		Human	PMID:15472229
Biological Process	GO:0008202	steroid metabolic process	UGT1A8	IDA		Human	PMID:16595710
Biological Process	GO:0008202	steroid metabolic process	UGT1A8	IDA		Human	PMID:23288867
Biological Process	GO:0052697	xenobiotic glucuronidation	UGT1A9	IDA		Human	PMID:20056724
Biological Process	GO:0052697	xenobiotic glucuronidation	UGT1A7	IDA		Human	PMID:20056724
Biological Process	GO:0052697	xenobiotic glucuronidation	UGT1A8	IDA		Human	PMID:20056724
Biological Process	GO:0006805	xenobiotic metabolic process	UGT1A9	IDA		Human	PMID:1910331

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern