Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UBXN1
  • Mouse genes Ubxn1
  • Rat genes Ubxn1
  • Zfish genes ubxn1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ubxn1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051117	ATPase binding	UBXN1	IPI	UniProtKB:P55072	Human	PMID:15362974
Molecular Function	GO:0051117	ATPase binding	UBXN1	IPI	UniProtKB:P55072	Human	PMID:21135095
Molecular Function	GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	UBXN1	IDA		Human	PMID:21135095
Molecular Function	GO:0071796	K6-linked polyubiquitin modification-dependent protein binding	UBXN1	IDA		Human	PMID:20351172
Molecular Function	GO:0031593	polyubiquitin modification-dependent protein binding	UBXN1	IDA		Human	PMID:15362974
Molecular Function	GO:1904855	proteasome regulatory particle binding	UBXN1	IDA		Human	PMID:15362974
Molecular Function	GO:0005515	protein binding	UBXN1	IPI	UniProtKB:Q9Y263	Human	PMID:18775313
Molecular Function	GO:0005515	protein binding	UBXN1	IPI	UniProtKB:P38398	Human	PMID:20351172
Molecular Function	GO:0005515	protein binding	UBXN1	IPI	UniProtKB:Q99728	Human	PMID:20351172
Molecular Function	GO:0005515	protein binding	UBXN1	IPI	UniProtKB:Q7KZS0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UBXN1	IPI	UniProtKB:Q8WU02	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UBXN1	IPI	UniProtKB:Q9HCM9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UBXN1	IPI	UniProtKB:Q9UMX0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UBXN1	IPI	UniProtKB:Q9UMX0-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UBXN1	IPI	UniProtKB:Q9Y263	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UBXN1	IPI	UniProtKB:V9HW80	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Ubxn1	IPI	RGD:620705	Rat	PMID:15944415|RGD:2302220
Molecular Function	GO:0043130	ubiquitin binding	UBXN1	IDA		Human	PMID:18775313
Molecular Function	GO:0031625	ubiquitin protein ligase binding	UBXN1	IDA		Human	PMID:18775313
Cellular Component	GO:0005737	cytoplasm	UBXN1	IDA		Human	PMID:10942595
Cellular Component	GO:0005737	cytoplasm	Ubxn1	IDA		Rat	PMID:15944415|RGD:2302220
Cellular Component	GO:0005829	cytosol	UBXN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	UBXN1	IDA		Human	PMID:21135095
Cellular Component	GO:0030425	dendrite	Ubxn1	IDA		Rat	PMID:15944415|RGD:2302220
Cellular Component	GO:0005783	endoplasmic reticulum	UBXN1	IDA		Human	PMID:21135095
Cellular Component	GO:0043025	neuronal cell body	Ubxn1	IDA		Rat	PMID:15944415|RGD:2302220
Cellular Component	GO:0005654	nucleoplasm	UBXN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Ubxn1	IDA		Rat	PMID:15944415|RGD:2302220
Cellular Component	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	UBXN1	IDA		Human	PMID:18775313
Biological Process	GO:1904293	negative regulation of ERAD pathway	UBXN1	IMP		Human	PMID:21135095
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	UBXN1	IDA		Human	PMID:20351172
Biological Process	GO:1903094	negative regulation of protein K48-linked deubiquitination	UBXN1	IDA		Human	PMID:21135095
Biological Process	GO:0031397	negative regulation of protein ubiquitination	UBXN1	IDA		Human	PMID:20351172
Biological Process	GO:2000157	negative regulation of ubiquitin-specific protease activity	UBXN1	IDA		Human	PMID:21135095

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern