Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TSPAN6
  • Mouse genes Tspan6
  • Rat genes Tspan6
  • Zfish genes tspan7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tspan6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TSPAN6	IPI	UniProtKB:Q7Z434	Human	PMID:22908223
Molecular Function	GO:0005515	protein binding	TSPAN6	IPI	UniProtKB:Q86WV6	Human	PMID:22908223
Molecular Function	GO:0005515	protein binding	TSPAN6	IPI	UniProtKB:Q9BYX4	Human	PMID:22908223
Molecular Function	GO:0005515	protein binding	TSPAN6	IPI	UniProtKB:Q9UL19	Human	PMID:22908223
Cellular Component	GO:0070062	extracellular exosome	TSPAN6	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	TSPAN6	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	TSPAN6	HDA		Human	PMID:23533145
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	TSPAN6	IDA		Human	PMID:22908223
Biological Process	GO:0039532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	TSPAN6	IMP		Human	PMID:22908223
Biological Process	GO:0070925	organelle assembly	tspan7	IMP	ZFIN:ZDB-GENO-200709-6	Zfish	PMID:31371827
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	TSPAN6	HMP		Human	PMID:12761501

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern