Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TSPAN5
  • Mouse genes Tspan5
  • Rat genes Tspan5
  • Zfish genes tspan5a,tspan5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tspan5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	TSPAN5	IPI	UniProtKB:O14672	Human	PMID:23091066
Molecular Function	GO:0019899	enzyme binding	Tspan5	IPI	UniProtKB:Q10741	Mouse	MGI:MGI:5567902|PMID:23035126
Molecular Function	GO:0005515	protein binding	TSPAN5	IPI	UniProtKB:O14672	Human	PMID:23091066
Molecular Function	GO:0005515	protein binding	TSPAN5	IPI	UniProtKB:O14672	Human	PMID:26686862
Cellular Component	GO:0015629	actin cytoskeleton	TSPAN5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	TSPAN5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	TSPAN5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	TSPAN5	IDA		Human	PMID:23091066
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	TSPAN5	IMP		Human	PMID:23091066
Biological Process	GO:0072659	protein localization to plasma membrane	TSPAN5	IMP		Human	PMID:23091066
Biological Process	GO:0051604	protein maturation	TSPAN5	IMP		Human	PMID:23091066
Biological Process	GO:0051604	protein maturation	Tspan5	IDA		Mouse	MGI:MGI:5567902|PMID:23035126

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern