Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TOE1
  • Mouse genes Toe1
  • Rat genes Toe1
  • Zfish genes toe1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Toe1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000175	3'-5'-RNA exonuclease activity	TOE1	IDA		Human	PMID:17178830
Molecular Function	GO:0004535	poly(A)-specific ribonuclease activity	TOE1	IDA		Human	PMID:17178830
Molecular Function	GO:0005515	protein binding	TOE1	IPI	UniProtKB:P04637	Human	PMID:19508870
Molecular Function	GO:0005515	protein binding	TOE1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0017069	snRNA binding	TOE1	IDA		Human	PMID:28092684
Cellular Component	GO:0015030	Cajal body	TOE1	IDA		Human	PMID:17178830
Cellular Component	GO:0005737	cytoplasm	TOE1	IDA		Human	PMID:17178830
Cellular Component	GO:0016604	nuclear body	TOE1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	TOE1	IDA		Human	GO_REF:0000052
Biological Process	GO:0007420	brain development	toe1	IMP	ZFIN:ZDB-MRPHLNO-170426-1	Zfish	PMID:28092684
Biological Process	GO:0007420	brain development	toe1	IMP	ZFIN:ZDB-MRPHLNO-170427-1	Zfish	PMID:28092684
Biological Process	GO:0070050	neuron cellular homeostasis	toe1	IMP	ZFIN:ZDB-MRPHLNO-170427-1	Zfish	PMID:28092684
Biological Process	GO:0070050	neuron cellular homeostasis	toe1	IMP	ZFIN:ZDB-MRPHLNO-170426-1	Zfish	PMID:28092684
Biological Process	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	TOE1	IDA		Human	PMID:17178830
Biological Process	GO:0034472	snRNA 3'-end processing	TOE1	IMP		Human	PMID:28092684

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern