Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TNNI2
  • Mouse genes Tnni2
  • Rat genes Tnni2
  • Zfish genes tnni2a.1,tnni2a.2,tnni2a.3,tnni2a.4,tnni2b.1,tnni2b.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tnni2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	TNNI2	IDA		Human	PMID:17194691
Molecular Function	GO:0005515	protein binding	TNNI2	IPI	UniProtKB:P11474	Human	PMID:18331830
Molecular Function	GO:0005515	protein binding	TNNI2	IPI	UniProtKB:P11474	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNNI2	IPI	UniProtKB:P13805-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNNI2	IPI	UniProtKB:P62195	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNNI2	IPI	UniProtKB:P62508-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNNI2	IPI	UniProtKB:Q5VUJ9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNNI2	IPI	UniProtKB:Q8NEH6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNNI2	IPI	UniProtKB:Q8TEB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNNI2	IPI	UniProtKB:Q9NX04	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNNI2	IPI	UniProtKB:Q9UI47-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNNI2	IPI	UniProtKB:Q9Y5B8	Human	PMID:32296183
Molecular Function	GO:0031014	troponin T binding	TNNI2	IPI	UniProtKB:P45378	Human	PMID:17194691
Cellular Component	GO:0005634	nucleus	TNNI2	IDA		Human	PMID:18331830
Cellular Component	GO:0005861	troponin complex	TNNI2	IDA		Human	PMID:17194691
Cellular Component	GO:0005861	troponin complex	Tnni2	IDA		Rat	PMID:16192301|RGD:1599030
Biological Process	GO:0030239	myofibril assembly	tnni2a.4	IMP	ZFIN:ZDB-GENO-100507-15	Zfish	PMID:21245197
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	TNNI2	IDA		Human	PMID:18331830
Biological Process	GO:0006937	regulation of muscle contraction	Tnni2	IDA		Rat	PMID:16192301|RGD:1599030
Biological Process	GO:0003009	skeletal muscle contraction	TNNI2	IDA		Human	PMID:17194691

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern