Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TNFAIP8L3
  • Mouse genes Tnfaip8l3
  • Rat genes Tnfaip8l3
  • Zfish genes tnfaip8l3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tnfaip8l3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035091	phosphatidylinositol binding	Tnfaip8l3	IDA		Mouse	MGI:MGI:5613301|PMID:25242044
Molecular Function	GO:0008526	phosphatidylinositol transfer activity	Tnfaip8l3	IMP		Mouse	MGI:MGI:5613301|PMID:25242044
Molecular Function	GO:0005515	protein binding	TNFAIP8L3	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFAIP8L3	IPI	UniProtKB:Q9Y3M2	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	TNFAIP8L3	IDA		Human	PMID:25479791
Cellular Component	GO:0005737	cytoplasm	Tnfaip8l3	IDA		Mouse	MGI:MGI:5645188|PMID:25479791
Cellular Component	GO:0005829	cytosol	TNFAIP8L3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	TNFAIP8L3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Tnfaip8l3	IDA		Mouse	MGI:MGI:5613301|PMID:25242044
Biological Process	GO:0048017	inositol lipid-mediated signaling	Tnfaip8l3	IDA		Mouse	MGI:MGI:5613301|PMID:25242044
Biological Process	GO:0015914	phospholipid transport	Tnfaip8l3	IDA		Mouse	MGI:MGI:5613301|PMID:25242044
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Tnfaip8l3	IDA		Mouse	MGI:MGI:5613301|PMID:25242044
Biological Process	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	Tnfaip8l3	IDA		Mouse	MGI:MGI:5613301|PMID:25242044
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	Tnfaip8l3	IDA		Mouse	MGI:MGI:5613301|PMID:25242044
Biological Process	GO:0019216	regulation of lipid metabolic process	Tnfaip8l3	IDA		Mouse	MGI:MGI:5613301|PMID:25242044

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern