Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TMEM33
  • Mouse genes Tmem33
  • Rat genes Tmem33
  • Zfish genes tmem33
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tmem33

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TMEM33	IPI	UniProtKB:P48039	Human	PMID:17215244
Molecular Function	GO:0005515	protein binding	TMEM33	IPI	UniProtKB:O75298-2|UniProtKB:Q15041|UniProtKB:Q16799-1	Human	PMID:25612671
Molecular Function	GO:0005515	protein binding	TMEM33	IPI	UniProtKB:Q9ES97-3	Human	PMID:25612671
Molecular Function	GO:0005515	protein binding	TMEM33	IPI	UniProtKB:Q9NZJ5	Human	PMID:26268696
Molecular Function	GO:0005515	protein binding	TMEM33	IPI	UniProtKB:P48039	Human	PMID:26514267
Molecular Function	GO:0005515	protein binding	TMEM33	IPI	UniProtKB:P48039	Human	PMID:28298427
Molecular Function	GO:0005515	protein binding	TMEM33	IPI	UniProtKB:Q96FB2	Human	PMID:32296183
Cellular Component	GO:0005783	endoplasmic reticulum	TMEM33	IDA		Human	PMID:25612671
Cellular Component	GO:0005789	endoplasmic reticulum membrane	TMEM33	IDA		Human	PMID:25612671
Cellular Component	GO:0005789	endoplasmic reticulum membrane	TMEM33	IDA		Human	PMID:26268696
Cellular Component	GO:0042470	melanosome	TMEM33	IDA		Human	PMID:17081065
Cellular Component	GO:0005635	nuclear envelope	TMEM33	IDA		Human	PMID:25612671
Biological Process	GO:1903896	positive regulation of IRE1-mediated unfolded protein response	TMEM33	IDA		Human	PMID:26268696
Biological Process	GO:1903899	positive regulation of PERK-mediated unfolded protein response	TMEM33	IDA		Human	PMID:26268696
Biological Process	GO:1903371	regulation of endoplasmic reticulum tubular network organization	TMEM33	IDA		Human	PMID:25612671
Biological Process	GO:1903670	regulation of sprouting angiogenesis	tmem33	IMP	ZFIN:ZDB-CRISPR-190716-3,ZFIN:ZDB-CRISPR-190716-4,ZFIN:ZDB-GENO-191017-2	Zfish	PMID:30760708
Biological Process	GO:1901339	regulation of store-operated calcium channel activity	tmem33	IMP	ZFIN:ZDB-CRISPR-190716-3,ZFIN:ZDB-CRISPR-190716-4,ZFIN:ZDB-GENO-191017-2	Zfish	PMID:30760708
Biological Process	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	tmem33	IMP	ZFIN:ZDB-CRISPR-190716-3,ZFIN:ZDB-CRISPR-190716-4,ZFIN:ZDB-GENO-191017-2	Zfish	PMID:30760708
Biological Process	GO:0034976	response to endoplasmic reticulum stress	TMEM33	IDA		Human	PMID:26268696

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern