Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TMEM18
  • Mouse genes Tmem18
  • Rat genes Tmem18
  • Zfish genes tmem18
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tmem18

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Tmem18	IPI	UniProtKB:Q9BTX1	Mouse	PMID:28811369
Molecular Function	GO:0005515	protein binding	Tmem18	IPI	UniProtKB:Q9NRG9	Mouse	PMID:28811369
Cellular Component	GO:0031965	nuclear membrane	TMEM18	IDA		Human	PMID:18559506
Cellular Component	GO:0031965	nuclear membrane	Tmem18	IDA		Mouse	PMID:28811369
Biological Process	GO:0016477	cell migration	TMEM18	IDA		Human	PMID:18559506
Biological Process	GO:0016477	cell migration	Tmem18	IDA		Rat	PMID:18559506|RGD:8553630
Biological Process	GO:0042755	eating behavior	Tmem18	IMP	MGI:MGI:4842746	Mouse	PMID:28811369
Biological Process	GO:0097009	energy homeostasis	Tmem18	IMP	MGI:MGI:4842746	Mouse	PMID:28811369
Biological Process	GO:0045444	fat cell differentiation	tmem18	IMP	ZFIN:ZDB-MRPHLNO-210608-1	Zfish	PMID:33086065

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern