Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TMEM168
  • Mouse genes Tmem168
  • Rat genes Tmem168
  • Zfish genes tmem168a,tmem168b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tmem168

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0017080	sodium channel regulator activity	TMEM168	IMP		Human	PMID:32175648
Cellular Component	GO:0031965	nuclear membrane	TMEM168	IDA		Human	PMID:32175648
Cellular Component	GO:0031965	nuclear membrane	Tmem168	IDA		Mouse	PMID:32175648
Cellular Component	GO:0030133	transport vesicle	TMEM168	IDA		Human	GO_REF:0000054
Biological Process	GO:2000058	regulation of ubiquitin-dependent protein catabolic process	Tmem168	IMP		Mouse	PMID:32175648
Biological Process	GO:1905150	regulation of voltage-gated sodium channel activity	Tmem168	IMP		Mouse	PMID:32175648

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern