Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TICRR
  • Mouse genes Ticrr
  • Rat genes Ticrr
  • Zfish genes ticrr
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ticrr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	TICRR	IDA		Human	PMID:20080954
Molecular Function	GO:0005515	protein binding	TICRR	IPI	UniProtKB:Q92547	Human	PMID:20080954
Molecular Function	GO:0005515	protein binding	TICRR	IPI	UniProtKB:P12004,UniProtKB:P33993,UniProtKB:P49736,UniProtKB:Q9NYP3	Human	PMID:28191891
Cellular Component	GO:0005829	cytosol	TICRR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	TICRR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	TICRR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TICRR	IDA		Human	PMID:20080954
Biological Process	GO:0006281	DNA repair	ticrr	IMP		Zfish	PMID:20080954|ZFIN:ZDB-PUB-100119-22
Biological Process	GO:0006260	DNA replication	ticrr	IMP		Zfish	PMID:20080954|ZFIN:ZDB-PUB-100119-22
Biological Process	GO:0007093	mitotic cell cycle checkpoint signaling	ticrr	IMP	ZFIN:ZDB-GENO-100428-1	Zfish	PMID:20080954
Biological Process	GO:0007093	mitotic cell cycle checkpoint signaling	ticrr	IMP	ZFIN:ZDB-GENO-100428-2	Zfish	PMID:20080954
Biological Process	GO:0033314	mitotic DNA replication checkpoint signaling	ticrr	IMP		Zfish	PMID:20080954|ZFIN:ZDB-PUB-100119-22
Biological Process	GO:0007095	mitotic G2 DNA damage checkpoint signaling	ticrr	IMP		Zfish	PMID:20080954|ZFIN:ZDB-PUB-100119-22
Biological Process	GO:0007095	mitotic G2 DNA damage checkpoint signaling	ticrr	IMP	ZFIN:ZDB-GENO-100428-1	Zfish	PMID:20080954
Biological Process	GO:0007095	mitotic G2 DNA damage checkpoint signaling	ticrr	IMP	ZFIN:ZDB-GENO-100428-2	Zfish	PMID:20080954
Biological Process	GO:0030174	regulation of DNA-templated DNA replication initiation	TICRR	IMP		Human	PMID:20116089
Biological Process	GO:0010212	response to ionizing radiation	ticrr	IMP		Zfish	PMID:20080954|ZFIN:ZDB-PUB-100119-22
Biological Process	GO:0010212	response to ionizing radiation	ticrr	IMP	ZFIN:ZDB-GENO-100428-1	Zfish	PMID:20080954
Biological Process	GO:0010212	response to ionizing radiation	ticrr	IMP	ZFIN:ZDB-GENO-100428-2	Zfish	PMID:20080954

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern