Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes THSD7A
  • Mouse genes Thsd7a
  • Rat genes Thsd7a
  • Zfish genes thsd7aa,thsd7ab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Thsd7a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	THSD7A	IPI	UniProtKB:P20138	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THSD7A	IPI	UniProtKB:P21964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THSD7A	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THSD7A	IPI	UniProtKB:Q3SXY8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THSD7A	IPI	UniProtKB:Q3ZAQ7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THSD7A	IPI	UniProtKB:Q71RG4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THSD7A	IPI	UniProtKB:Q7Z5P4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THSD7A	IPI	UniProtKB:Q86WI0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THSD7A	IPI	UniProtKB:Q8NBJ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THSD7A	IPI	UniProtKB:Q9NY72	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THSD7A	IPI	UniProtKB:Q9NYP7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THSD7A	IPI	UniProtKB:Q9Y5Y7	Human	PMID:32296183
Cellular Component	GO:0005886	plasma membrane	THSD7A	IDA		Human	PMID:27214550
Cellular Component	GO:0005886	plasma membrane	Thsd7a	IDA		Mouse	MGI:MGI:6154547|PMID:27214550
Cellular Component	GO:0098846	podocyte foot	Thsd7a	IDA		Mouse	MGI:MGI:6154547|PMID:27214550
Biological Process	GO:0031532	actin cytoskeleton reorganization	Thsd7a	IMP		Mouse	MGI:MGI:6154547|PMID:27214550
Biological Process	GO:0001525	angiogenesis	thsd7aa	IMP	ZFIN:ZDB-MRPHLNO-110531-1	Zfish	PMID:21520329
Biological Process	GO:0001525	angiogenesis	thsd7aa	IMP	ZFIN:ZDB-MRPHLNO-110531-2	Zfish	PMID:21520329
Biological Process	GO:0048675	axon extension	thsd7aa	IMP	ZFIN:ZDB-MRPHLNO-110531-1	Zfish	PMID:27484901
Biological Process	GO:0043534	blood vessel endothelial cell migration	thsd7aa	IMP	ZFIN:ZDB-MRPHLNO-110531-1	Zfish	PMID:21520329
Biological Process	GO:0043534	blood vessel endothelial cell migration	thsd7aa	IMP	ZFIN:ZDB-MRPHLNO-110531-2	Zfish	PMID:21520329
Biological Process	GO:0003094	glomerular filtration	thsd7aa	IMP	ZFIN:ZDB-MRPHLNO-180405-4	Zfish	PMID:28814510
Biological Process	GO:0032835	glomerulus development	thsd7aa	IMP	ZFIN:ZDB-MRPHLNO-180405-4	Zfish	PMID:28814510
Biological Process	GO:0072015	podocyte development	thsd7aa	IMP	ZFIN:ZDB-MRPHLNO-180405-4	Zfish	PMID:28814510
Biological Process	GO:0008593	regulation of Notch signaling pathway	thsd7aa	IMP	ZFIN:ZDB-MRPHLNO-110531-1	Zfish	PMID:27484901
Biological Process	GO:0002040	sprouting angiogenesis	thsd7aa	IMP	ZFIN:ZDB-MRPHLNO-110531-1	Zfish	PMID:27484901

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern