Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes THEM4
  • Mouse genes Them4
  • Rat genes Them4
  • Zfish genes them4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Them4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016290	palmitoyl-CoA hydrolase activity	THEM4	IDA		Human	PMID:22871024
Molecular Function	GO:0005515	protein binding	THEM4	IPI	UniProtKB:P31749	Human	PMID:19541650
Molecular Function	GO:0005515	protein binding	THEM4	IPI	UniProtKB:P31749	Human	PMID:22309289
Molecular Function	GO:0005515	protein binding	THEM4	IPI	UniProtKB:P31749	Human	PMID:24670654
Molecular Function	GO:0005515	protein binding	THEM4	IPI	UniProtKB:P01112	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	THEM4	IPI	UniProtKB:P08670	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	THEM4	IPI	UniProtKB:P16284	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	THEM4	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	THEM4	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	THEM4	IPI	UniProtKB:Q9Y649	Human	PMID:32814053
Cellular Component	GO:0005829	cytosol	THEM4	IDA		Human	PMID:19604401
Cellular Component	GO:0005739	mitochondrion	THEM4	IDA		Human	PMID:19604401
Cellular Component	GO:0005739	mitochondrion	Them4	HDA		Mouse	PMID:18614015
Biological Process	GO:0006631	fatty acid metabolic process	THEM4	IDA		Human	PMID:22871024
Biological Process	GO:0043491	protein kinase B signaling	THEM4	IMP		Human	PMID:19168129
Biological Process	GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	THEM4	IMP		Human	PMID:19168129

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern