Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TCOF1
  • Mouse genes Tcof1
  • Rat genes Tcof1
  • Zfish genes tcof1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tcof1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TCOF1	IPI	UniProtKB:P32121	Human	PMID:17620599
Molecular Function	GO:0005515	protein binding	TCOF1	IPI	UniProtKB:P49407	Human	PMID:17620599
Molecular Function	GO:0005515	protein binding	TCOF1	IPI	UniProtKB:P78362	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	TCOF1	IPI	UniProtKB:O60934	Human	PMID:25064736
Molecular Function	GO:0005515	protein binding	TCOF1	IPI	UniProtKB:Q8NFY9	Human	PMID:26399832
Molecular Function	GO:0005515	protein binding	TCOF1	IPI	UniProtKB:P78362	Human	PMID:32707033
Molecular Function	GO:0046982	protein heterodimerization activity	TCOF1	IPI	UniProtKB:Q14978	Human	PMID:26399832
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	TCOF1	IDA		Human	PMID:26399832
Molecular Function	GO:0003723	RNA binding	TCOF1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	TCOF1	HDA		Human	PMID:22681889
Molecular Function	GO:0097110	scaffold protein binding	TCOF1	IPI	UniProtKB:Q9H8X2	Human	PMID:23203802
Cellular Component	GO:0005829	cytosol	TCOF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0001650	fibrillar center	TCOF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	TCOF1	IDA		Human	PMID:15249688
Cellular Component	GO:0005730	nucleolus	TCOF1	IDA		Human	PMID:23203802
Cellular Component	GO:0005654	nucleoplasm	TCOF1	IDA		Human	GO_REF:0000052
Biological Process	GO:0014032	neural crest cell development	TCOF1	IMP		Human	PMID:26399832
Biological Process	GO:0014029	neural crest formation	TCOF1	IMP		Human	PMID:26399832
Biological Process	GO:0042790	nucleolar large rRNA transcription by RNA polymerase I	Tcof1	IMP	MGI:MGI:2386185	Mouse	PMID:15249688
Biological Process	GO:0006417	regulation of translation	TCOF1	IMP		Human	PMID:26399832

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern