Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TACR3
  • Mouse genes Tacr3
  • Rat genes Tacr3
  • Zfish genes tacr3a,tacr3l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tacr3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TACR3	IPI	UniProtKB:P20366:PRO_0000033534	Human	PMID:12716968
Molecular Function	GO:0005515	protein binding	TACR3	IPI	UniProtKB:Q9UHF0:PRO_0000033566	Human	PMID:12716968
Molecular Function	GO:0005515	protein binding	TACR3	IPI	UniProtKB:Q9UHF0:PRO_0000033566	Human	PMID:23597562
Molecular Function	GO:0004995	tachykinin receptor activity	Tacr3	IDA		Rat	PMID:1662278|RGD:2305982
Molecular Function	GO:0004995	tachykinin receptor activity	tacr3l	IDA		Zfish	PMID:22689988
Molecular Function	GO:0004995	tachykinin receptor activity	tacr3a	IDA		Zfish	PMID:22689988
Cellular Component	GO:0005737	cytoplasm	Tacr3	IDA		Rat	PMID:16357093|RGD:2305936
Cellular Component	GO:0032590	dendrite membrane	Tacr3	IDA		Rat	PMID:16357093|RGD:2305936
Cellular Component	GO:0016020	membrane	Tacr3	IDA		Rat	PMID:8788251|RGD:5147623
Cellular Component	GO:0032809	neuronal cell body membrane	Tacr3	IDA		Rat	PMID:16357093|RGD:2305936
Cellular Component	GO:0005634	nucleus	Tacr3	IDA		Rat	PMID:18583062|RGD:2305930
Cellular Component	GO:0097225	sperm midpiece	TACR3	IDA		Human	PMID:17437961
Biological Process	GO:0042538	hyperosmotic salinity response	Tacr3	IDA		Rat	PMID:18583062|RGD:2305930
Biological Process	GO:0007218	neuropeptide signaling pathway	tacr3a	IDA		Zfish	PMID:22689988|ZFIN:ZDB-PUB-120630-5
Biological Process	GO:0007218	neuropeptide signaling pathway	tacr3l	IDA		Zfish	PMID:22689988|ZFIN:ZDB-PUB-120630-5
Biological Process	GO:0045777	positive regulation of blood pressure	Tacr3	IDA		Rat	PMID:2478257|RGD:2305983
Biological Process	GO:1902093	positive regulation of flagellated sperm motility	TACR3	IMP		Human	PMID:17437961
Biological Process	GO:0010460	positive regulation of heart rate	Tacr3	IDA		Rat	PMID:2471579|RGD:2305984
Biological Process	GO:0070474	positive regulation of uterine smooth muscle contraction	Tacr3	IDA		Rat	PMID:12390879|RGD:2305937
Biological Process	GO:0042053	regulation of dopamine metabolic process	Tacr3	IDA		Rat	PMID:8574643|RGD:2305963
Biological Process	GO:0060259	regulation of feeding behavior	Tacr3	IDA		Rat	PMID:2462199|RGD:2305985
Biological Process	GO:0042220	response to cocaine	Tacr3	IMP		Rat	PMID:17445241|RGD:2305931
Biological Process	GO:0032355	response to estradiol	Tacr3	IEP		Rat	PMID:10342838|RGD:5147482
Biological Process	GO:0032355	response to estradiol	Tacr3	IDA		Rat	PMID:12390879|RGD:2305937
Biological Process	GO:0043278	response to morphine	Tacr3	IEP		Rat	PMID:7536308|RGD:2305965
Biological Process	GO:0007217	tachykinin receptor signaling pathway	tacr3l	IDA		Zfish	PMID:22689988|ZFIN:ZDB-PUB-120630-5
Biological Process	GO:0007217	tachykinin receptor signaling pathway	tacr3a	IDA		Zfish	PMID:22689988|ZFIN:ZDB-PUB-120630-5

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern