Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SYNPO
  • Mouse genes Synpo
  • Rat genes Synpo
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Synpo

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Synpo	IDA		Mouse	PMID:9314539
Molecular Function	GO:0005515	protein binding	SYNPO	IPI	UniProtKB:Q8IX03	Human	PMID:18596123
Molecular Function	GO:0005515	protein binding	SYNPO	IPI	UniProtKB:P12814	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	SYNPO	IPI	UniProtKB:P12814	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	SYNPO	IPI	UniProtKB:Q96ES7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYNPO	IPI	UniProtKB:Q99459	Human	PMID:32296183
Cellular Component	GO:0015629	actin cytoskeleton	SYNPO	IDA		Human	GO_REF:0000052
Cellular Component	GO:0015629	actin cytoskeleton	SYNPO	IDA		Human	GO_REF:0000054
Cellular Component	GO:0015629	actin cytoskeleton	Synpo	IDA		Mouse	PMID:9314539
Cellular Component	GO:0071944	cell periphery	Synpo	IDA		Mouse	PMID:25071083
Cellular Component	GO:0005829	cytosol	SYNPO	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	SYNPO	IDA		Human	PMID:30661770
Cellular Component	GO:0098978	glutamatergic synapse	Synpo	IDA		Mouse	PMID:12928494
Cellular Component	GO:0098978	glutamatergic synapse	Synpo	IMP		Mouse	PMID:12928494
Cellular Component	GO:0098978	glutamatergic synapse	Synpo	IDA		Mouse	PMID:25164660
Cellular Component	GO:0098978	glutamatergic synapse	Synpo	IMP		Mouse	PMID:25164660
Cellular Component	GO:0098978	glutamatergic synapse	Synpo	IDA		Rat	PMID:10701442|RGD:13702235
Cellular Component	GO:0005886	plasma membrane	SYNPO	IDA		Human	GO_REF:0000052
Cellular Component	GO:0098794	postsynapse	Synpo	IDA		Mouse	MGI:MGI:5607805|PMID:25164660
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Synpo	IDA		Mouse	PMID:12928494
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Synpo	IMP		Mouse	PMID:12928494
Cellular Component	GO:0097444	spine apparatus	Synpo	IDA		Mouse	MGI:MGI:2673780|PMID:12928494
Cellular Component	GO:0097444	spine apparatus	Synpo	IDA		Rat	PMID:10701442|RGD:13702235
Cellular Component	GO:0001725	stress fiber	Synpo	IDA		Mouse	MGI:MGI:3577135|PMID:15841212
Biological Process	GO:0098886	modification of dendritic spine	SYNPO	IDA		Human	PMID:25164660
Biological Process	GO:0032233	positive regulation of actin filament bundle assembly	Synpo	IDA		Mouse	MGI:MGI:3577135|PMID:15841212
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	Synpo	IMP		Mouse	PMID:12928494
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	Synpo	IDA		Mouse	PMID:12928494
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	Synpo	IDA		Mouse	PMID:25164660
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	Synpo	IMP		Mouse	PMID:25164660
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	Synpo	IMP		Mouse	MGI:MGI:2673780|PMID:12928494
Biological Process	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration	Synpo	IDA		Mouse	PMID:25164660
Biological Process	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration	Synpo	IMP		Mouse	PMID:25164660
Biological Process	GO:0051492	regulation of stress fiber assembly	Synpo	IDA		Mouse	MGI:MGI:3577135|PMID:15841212
Biological Process	GO:1905355	spine apparatus assembly	Synpo	IMP		Mouse	MGI:MGI:2673780|PMID:12928494
Biological Process	GO:0008542	visual learning	Synpo	IMP		Mouse	MGI:MGI:2673780|PMID:12928494

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern