Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes STXBP4
  • Mouse genes Stxbp4
  • Rat genes Stxbp4
  • Zfish genes stxbp4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Stxbp4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	STXBP4	IPI	UniProtKB:Q9H3D4	Human	PMID:19451233
Molecular Function	GO:0005515	protein binding	Stxbp4	IPI	PR:P70452	Mouse	PMID:10394363
Molecular Function	GO:0005515	protein binding	Stxbp4	IPI	PR:O09044	Mouse	PMID:10394363
Molecular Function	GO:0005515	protein binding	Stxbp4	IPI	PR:P63044	Mouse	PMID:10394363
Molecular Function	GO:0019905	syntaxin binding	STXBP4	IPI	UniProtKB:Q12846	Human	PMID:12855681
Cellular Component	GO:0070062	extracellular exosome	STXBP4	HDA		Human	PMID:19056867
Cellular Component	GO:0045335	phagocytic vesicle	Stxbp4	IDA		Mouse	PMID:19144319
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Stxbp4	IDA		Mouse	PMID:29874582
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Stxbp4	IMP		Mouse	PMID:29874582
Biological Process	GO:0071346	cellular response to type II interferon	Stxbp4	IDA		Mouse	PMID:19144319
Biological Process	GO:0006974	DNA damage response	STXBP4	IDA		Human	PMID:19451233
Biological Process	GO:0008286	insulin receptor signaling pathway	Stxbp4	IDA		Mouse	PMID:10394363
Biological Process	GO:1902808	positive regulation of cell cycle G1/S phase transition	STXBP4	IMP		Human	PMID:19451233
Biological Process	GO:0010838	positive regulation of keratinocyte proliferation	STXBP4	IMP		Human	PMID:19451233
Biological Process	GO:0050821	protein stabilization	STXBP4	IMP		Human	PMID:19451233
Biological Process	GO:0006605	protein targeting	Stxbp4	IDA		Mouse	PMID:10394363
Biological Process	GO:0010827	regulation of glucose transmembrane transport	Stxbp4	IDA		Mouse	PMID:10394363
Biological Process	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	STXBP4	IDA		Human	PMID:12855681
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Stxbp4	IDA		Mouse	PMID:29874582
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Stxbp4	IMP		Mouse	PMID:29874582

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern