Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes STMN1
  • Mouse genes Stmn1
  • Rat genes Stmn1
  • Zfish genes stmn1a,stmn1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Stmn1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	STMN1	IPI	UniProtKB:P46527	Human	PMID:15652749
Molecular Function	GO:0005515	protein binding	STMN1	IPI	UniProtKB:P46527	Human	PMID:21423803
Molecular Function	GO:0005515	protein binding	STMN1	IPI	UniProtKB:Q86VW0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Stmn1	IPI	UniProtKB:P97343	Mouse	MGI:MGI:1326817|PMID:7724523
Molecular Function	GO:0005515	protein binding	Stmn1	IPI	UniProtKB:P46414	Mouse	MGI:MGI:3529385|PMID:15652749
Molecular Function	GO:0015631	tubulin binding	STMN1	IDA		Human	PMID:10675326
Molecular Function	GO:0015631	tubulin binding	STMN1	IMP		Human	PMID:12860982
Cellular Component	GO:0005737	cytoplasm	Stmn1	IDA		Mouse	PMID:10369391
Cellular Component	GO:0005829	cytosol	STMN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Stmn1	IDA		Mouse	PMID:10712642
Cellular Component	GO:0070062	extracellular exosome	STMN1	HDA		Human	PMID:20458337
Cellular Component	GO:0016020	membrane	Stmn1	IDA		Mouse	PMID:10712642
Biological Process	GO:0007409	axonogenesis	Stmn1	IMP	MGI:MGI:2655259	Mouse	PMID:11839567
Biological Process	GO:0007420	brain development	Stmn1	IEP		Rat	PMID:2745432|RGD:730220
Biological Process	GO:0061436	establishment of skin barrier	STMN1	IMP		Human	PMID:25198505
Biological Process	GO:0048012	hepatocyte growth factor receptor signaling pathway	STMN1	IMP		Human	PMID:25198505
Biological Process	GO:0007019	microtubule depolymerization	STMN1	IDA		Human	PMID:9880330
Biological Process	GO:0007019	microtubule depolymerization	STMN1	IMP		Human	PMID:10675326
Biological Process	GO:0000281	mitotic cytokinesis	STMN1	IMP		Human	PMID:25122120
Biological Process	GO:0000281	mitotic cytokinesis	Stmn1	IGI	MGI:MGI:1335094	Mouse	PMID:25122120
Biological Process	GO:0007052	mitotic spindle organization	STMN1	IDA		Human	PMID:9271428
Biological Process	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity	STMN1	IMP		Human	PMID:25198505
Biological Process	GO:0031115	negative regulation of microtubule polymerization	STMN1	IMP		Human	PMID:25198505
Biological Process	GO:0031115	negative regulation of microtubule polymerization	Stmn1	IDA		Mouse	PMID:15652749
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	STMN1	IMP		Human	PMID:25198505
Biological Process	GO:0051497	negative regulation of stress fiber assembly	STMN1	IMP		Human	PMID:25198505
Biological Process	GO:0070495	negative regulation of thrombin-activated receptor signaling pathway	STMN1	IMP		Human	PMID:25198505
Biological Process	GO:0030334	regulation of cell migration	Stmn1	IGI	MGI:MGI:104565	Mouse	PMID:15652749
Biological Process	GO:0031110	regulation of microtubule polymerization or depolymerization	STMN1	IMP		Human	PMID:12860982
Biological Process	GO:0009615	response to virus	STMN1	IEP		Human	PMID:16548883

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern