Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPTSSA
  • Mouse genes Sptssa
  • Rat genes Sptssa
  • Zfish genes sptssa
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sptssa

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SPTSSA	IPI	UniProtKB:O15269	Human	PMID:19416851
Molecular Function	GO:0005515	protein binding	SPTSSA	IPI	UniProtKB:Q96N66	Human	PMID:23510452
Molecular Function	GO:0005515	protein binding	SPTSSA	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPTSSA	IPI	UniProtKB:O00258	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPTSSA	IPI	UniProtKB:O75783	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPTSSA	IPI	UniProtKB:Q9BSE4	Human	PMID:32296183
Molecular Function	GO:0004758	serine C-palmitoyltransferase activity	SPTSSA	IDA		Human	PMID:19416851
Molecular Function	GO:0004758	serine C-palmitoyltransferase activity	SPTSSA	IDA		Human	PMID:25691431
Cellular Component	GO:0005783	endoplasmic reticulum	SPTSSA	IDA		Human	PMID:23510452
Cellular Component	GO:0017059	serine C-palmitoyltransferase complex	SPTSSA	IPI		Human	PMID:19416851
Cellular Component	GO:0017059	serine C-palmitoyltransferase complex	SPTSSA	IPI		Human	PMID:33558761
Cellular Component	GO:0017059	serine C-palmitoyltransferase complex	SPTSSA	IDA		Human	PMID:19416851
Biological Process	GO:0046513	ceramide biosynthetic process	SPTSSA	IDA		Human	PMID:25691431
Biological Process	GO:0008104	protein localization	SPTSSA	IDA		Human	PMID:23510452
Biological Process	GO:0046512	sphingosine biosynthetic process	SPTSSA	IDA		Human	PMID:19416851
Biological Process	GO:0046512	sphingosine biosynthetic process	SPTSSA	IDA		Human	PMID:33558761

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern