Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPTB
  • Mouse genes Sptb
  • Rat genes Sptb
  • Zfish genes sptb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sptb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Sptb	IDA		Mouse	PMID:20585040
Molecular Function	GO:0051015	actin filament binding	SPTB	IDA		Human	PMID:16060676
Molecular Function	GO:0051015	actin filament binding	Sptb	IDA		Mouse	PMID:20585040
Molecular Function	GO:0030506	ankyrin binding	SPTB	IPI	UniProtKB:P16157	Human	PMID:8159688
Molecular Function	GO:0005515	protein binding	SPTB	IPI	UniProtKB:P50463	Human	PMID:10751147
Molecular Function	GO:0005515	protein binding	SPTB	IPI	UniProtKB:P02549	Human	PMID:12820899
Molecular Function	GO:0005515	protein binding	SPTB	IPI	UniProtKB:P11171	Human	PMID:16060676
Molecular Function	GO:0005515	protein binding	SPTB	IPI	UniProtKB:P02549	Human	PMID:20197550
Molecular Function	GO:0005515	protein binding	SPTB	IPI	UniProtKB:O95295	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	SPTB	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Sptb	IPI	PR:P08032	Mouse	PMID:20585040
Cellular Component	GO:0030863	cortical cytoskeleton	Sptb	IDA		Mouse	PMID:18723693
Cellular Component	GO:0005829	cytosol	SPTB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0098978	glutamatergic synapse	SPTB	IDA		Human	PMID:21297961
Cellular Component	GO:0098978	glutamatergic synapse	SPTB	IMP		Human	PMID:21297961
Cellular Component	GO:0098978	glutamatergic synapse	Sptb	IDA		Rat	PMID:11454415|RGD:155230707
Cellular Component	GO:0016020	membrane	Sptb	IDA		Mouse	PMID:18723693
Cellular Component	GO:0005886	plasma membrane	Sptb	IDA		Mouse	PMID:14627610
Cellular Component	GO:0098794	postsynapse	Sptb	IDA		Rat	PMID:11454415|RGD:155230707
Cellular Component	GO:0032991	protein-containing complex	SPTB	IDA		Human	PMID:16060676
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	SPTB	IDA		Human	PMID:379653
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	Sptb	IMP	MGI:MGI:1856378	Mouse	PMID:6234993
Biological Process	GO:0035162	embryonic hemopoiesis	sptb	IMP	ZFIN:ZDB-GENO-001229-2	Zfish	PMID:9007251
Biological Process	GO:0048821	erythrocyte development	sptb	IMP	ZFIN:ZDB-GENO-001229-2	Zfish	PMID:11060238
Biological Process	GO:0030097	hemopoiesis	Sptb	IMP	MGI:MGI:1856378	Mouse	PMID:9373273
Biological Process	GO:0098885	modification of postsynaptic actin cytoskeleton	SPTB	IDA		Human	PMID:21297961
Biological Process	GO:0098885	modification of postsynaptic actin cytoskeleton	SPTB	IMP		Human	PMID:21297961
Biological Process	GO:0007009	plasma membrane organization	Sptb	IMP	MGI:MGI:1856378	Mouse	PMID:9373263
Biological Process	GO:0006779	porphyrin-containing compound biosynthetic process	Sptb	IMP	MGI:MGI:1856378	Mouse	PMID:658175

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern