Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPTA1
  • Mouse genes Spta1
  • Rat genes Spta1
  • Zfish genes sptbn4a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Spta1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SPTA1	IPI	UniProtKB:P11277	Human	PMID:12820899
Molecular Function	GO:0005515	protein binding	SPTA1	IPI	UniProtKB:Q01082	Human	PMID:12820899
Molecular Function	GO:0005515	protein binding	SPTA1	IPI	UniProtKB:P11277	Human	PMID:20197550
Molecular Function	GO:0005515	protein binding	SPTA1	IPI	UniProtKB:A8MYP8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPTA1	IPI	UniProtKB:O14874	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPTA1	IPI	UniProtKB:O95678	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPTA1	IPI	UniProtKB:Q0VAL7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPTA1	IPI	UniProtKB:Q5BKZ1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPTA1	IPI	UniProtKB:Q8N715	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPTA1	IPI	UniProtKB:Q8TAE8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPTA1	IPI	UniProtKB:Q99757	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPTA1	IPI	UniProtKB:Q99959-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPTA1	IPI	UniProtKB:Q9BY27	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPTA1	IPI	UniProtKB:Q9NQT4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPTA1	IPI	UniProtKB:Q9NRE2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPTA1	IPI	UniProtKB:Q8IZP0	Human	PMID:9593709
Molecular Function	GO:0005515	protein binding	Spta1	IPI	MGI:MGI:98387	Mouse	PMID:20585040
Cellular Component	GO:0030424	axon	Spta1	IDA		Rat	PMID:11684331|RGD:11059525
Cellular Component	GO:0030863	cortical cytoskeleton	Spta1	IDA		Mouse	PMID:18723693
Cellular Component	GO:0032437	cuticular plate	Spta1	IDA		Mouse	PMID:20016102
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	Spta1	IDA		Rat	PMID:11684331|RGD:11059525
Cellular Component	GO:0016020	membrane	Spta1	IDA		Mouse	PMID:18723693
Cellular Component	GO:0008091	spectrin	Spta1	IMP	MGI:MGI:1858128	Mouse	PMID:6234993
Cellular Component	GO:0008091	spectrin	Spta1	IMP	MGI:MGI:1856181	Mouse	PMID:6234993
Cellular Component	GO:0008091	spectrin	Spta1	IMP	MGI:MGI:1856377	Mouse	PMID:6234993
Cellular Component	GO:0008091	spectrin	Spta1	IMP	MGI:MGI:1856180	Mouse	PMID:6234993
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	SPTA1	IDA		Human	PMID:379653
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	Spta1	IMP	MGI:MGI:1856181	Mouse	PMID:6841965
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	Spta1	IMP	MGI:MGI:1858128	Mouse	PMID:6234993
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	Spta1	IMP	MGI:MGI:1856181	Mouse	PMID:6234993
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	Spta1	IMP	MGI:MGI:1856180	Mouse	PMID:6234993
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	Spta1	IMP	MGI:MGI:1856377	Mouse	PMID:6234993
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	Spta1	IMP	MGI:MGI:1856180	Mouse	PMID:6841965
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	Spta1	IMP	MGI:MGI:1856377	Mouse	PMID:6841965
Biological Process	GO:0030036	actin cytoskeleton organization	Spta1	IMP	MGI:MGI:1856377	Mouse	PMID:8195289
Biological Process	GO:0030097	hemopoiesis	Spta1	IMP	MGI:MGI:1856181	Mouse	PMID:6841965
Biological Process	GO:0030097	hemopoiesis	Spta1	IMP	MGI:MGI:1856377	Mouse	PMID:7059672
Biological Process	GO:0030097	hemopoiesis	Spta1	IMP	MGI:MGI:1856181	Mouse	PMID:7059672
Biological Process	GO:0030097	hemopoiesis	Spta1	IMP	MGI:MGI:1856377	Mouse	PMID:11920196
Biological Process	GO:0030097	hemopoiesis	Spta1	IMP	MGI:MGI:1856377	Mouse	PMID:6841965
Biological Process	GO:0030097	hemopoiesis	Spta1	IMP	MGI:MGI:1856180	Mouse	PMID:6841965
Biological Process	GO:0002260	lymphocyte homeostasis	Spta1	IMP	MGI:MGI:1856181	Mouse	PMID:1934076
Biological Process	GO:0007009	plasma membrane organization	Spta1	IMP	MGI:MGI:1856377	Mouse	PMID:6841965
Biological Process	GO:0007009	plasma membrane organization	Spta1	IMP	MGI:MGI:1856180	Mouse	PMID:6841965
Biological Process	GO:0007009	plasma membrane organization	Spta1	IMP	MGI:MGI:1856181	Mouse	PMID:6841965
Biological Process	GO:0006779	porphyrin-containing compound biosynthetic process	Spta1	IMP	MGI:MGI:1856377	Mouse	PMID:658175
Biological Process	GO:0006779	porphyrin-containing compound biosynthetic process	Spta1	IMP	MGI:MGI:1856181	Mouse	PMID:658175
Biological Process	GO:0032092	positive regulation of protein binding	Spta1	IGI	MGI:MGI:98387	Mouse	PMID:20585040
Biological Process	GO:0032092	positive regulation of protein binding	Spta1	IGI	MGI:MGI:95401	Mouse	PMID:20585040
Biological Process	GO:0042102	positive regulation of T cell proliferation	Spta1	IMP	MGI:MGI:1856181	Mouse	PMID:7684329
Biological Process	GO:0008360	regulation of cell shape	Spta1	IMP	MGI:MGI:1856377	Mouse	PMID:8195289

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern