Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPIDR
  • Mouse genes Spidr
  • Rat genes Spidr
  • Zfish genes spidr
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Spidr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SPIDR	IPI	UniProtKB:P54132	Human	PMID:23509288
Molecular Function	GO:0005515	protein binding	SPIDR	IPI	UniProtKB:Q06609	Human	PMID:23509288
Molecular Function	GO:0005515	protein binding	SPIDR	IPI	UniProtKB:Q6PIW4	Human	PMID:23754376
Cellular Component	GO:0000228	nuclear chromosome	SPIDR	IDA		Human	PMID:23509288
Cellular Component	GO:0005654	nucleoplasm	SPIDR	IDA		Human	GO_REF:0000052
Biological Process	GO:0072757	cellular response to camptothecin	SPIDR	IDA		Human	PMID:23509288
Biological Process	GO:0072711	cellular response to hydroxyurea	SPIDR	IDA		Human	PMID:23509288
Biological Process	GO:0071479	cellular response to ionizing radiation	SPIDR	IDA		Human	PMID:23509288
Biological Process	GO:0071479	cellular response to ionizing radiation	SPIDR	IDA		Human	PMID:23754376
Biological Process	GO:0006974	DNA damage response	SPIDR	IDA		Human	PMID:23509288
Biological Process	GO:0000724	double-strand break repair via homologous recombination	SPIDR	IMP		Human	PMID:23509288
Biological Process	GO:0000724	double-strand break repair via homologous recombination	SPIDR	IMP		Human	PMID:27967308
Biological Process	GO:0000724	double-strand break repair via homologous recombination	SPIDR	IMP		Human	PMID:34697795
Biological Process	GO:2000781	positive regulation of double-strand break repair	SPIDR	IMP		Human	PMID:23509288
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	SPIDR	IDA		Human	PMID:23509288
Biological Process	GO:0010569	regulation of double-strand break repair via homologous recombination	SPIDR	IDA		Human	PMID:23754376
Biological Process	GO:0070202	regulation of establishment of protein localization to chromosome	SPIDR	IDA		Human	PMID:23509288

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern