Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPICE1
  • Mouse genes Spice1
  • Rat genes Spice1
  • Zfish genes spice1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Spice1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SPICE1	IPI	UniProtKB:O60341	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	SPICE1	IPI	UniProtKB:Q66GS9	Human	PMID:26638075
Molecular Function	GO:0005515	protein binding	SPICE1	IPI	UniProtKB:O60341	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPICE1	IPI	UniProtKB:P61764	Human	PMID:32296183
Cellular Component	GO:0005814	centriole	SPICE1	IDA		Human	PMID:20736305
Cellular Component	GO:0005813	centrosome	SPICE1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005813	centrosome	SPICE1	IDA		Human	PMID:21399614
Cellular Component	GO:0005819	spindle	SPICE1	IDA		Human	PMID:20736305
Biological Process	GO:0051310	metaphase plate congression	SPICE1	IMP		Human	PMID:20736305
Biological Process	GO:0090307	mitotic spindle assembly	SPICE1	IMP		Human	PMID:20736305
Biological Process	GO:0046599	regulation of centriole replication	SPICE1	IMP		Human	PMID:20736305

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern