Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPEF2
  • Mouse genes Spef2
  • Rat genes Spef2
  • Zfish genes spef2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Spef2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Spef2	IPI	PR:Q61025	Mouse	PMID:19889948
Cellular Component	GO:0005737	cytoplasm	Spef2	IDA		Mouse	PMID:19889948
Cellular Component	GO:0005794	Golgi apparatus	Spef2	IDA		Mouse	PMID:19889948
Cellular Component	GO:0002177	manchette	Spef2	IDA		Mouse	PMID:19889948
Cellular Component	GO:0036126	sperm flagellum	SPEF2	IDA		Human	PMID:31048344
Cellular Component	GO:0036126	sperm flagellum	SPEF2	IDA		Human	PMID:31151990
Cellular Component	GO:0036126	sperm flagellum	SPEF2	IDA		Human	PMID:31278745
Cellular Component	GO:0097225	sperm midpiece	Spef2	IDA		Mouse	PMID:19889948
Biological Process	GO:0048854	brain morphogenesis	Spef2	IMP	MGI:MGI:5295267	Mouse	PMID:21715716
Biological Process	GO:0090660	cerebrospinal fluid circulation	Spef2	IGI	MGI:MGI:1922208	Mouse	PMID:32704025
Biological Process	GO:0090660	cerebrospinal fluid circulation	Spef2	IGI	MGI:MGI:2684947	Mouse	PMID:32704025
Biological Process	GO:0003351	epithelial cilium movement involved in extracellular fluid movement	Spef2	IMP	MGI:MGI:5295267	Mouse	PMID:21715716
Biological Process	GO:0051649	establishment of localization in cell	Spef2	IGI	MGI:MGI:2684947	Mouse	PMID:32704025
Biological Process	GO:0051649	establishment of localization in cell	Spef2	IGI	MGI:MGI:1922208	Mouse	PMID:32704025
Biological Process	GO:0120197	mucociliary clearance	Spef2	IGI	MGI:MGI:1922208	Mouse	PMID:32704025
Biological Process	GO:0120197	mucociliary clearance	Spef2	IGI	MGI:MGI:2684947	Mouse	PMID:32704025
Biological Process	GO:0120197	mucociliary clearance	Spef2	IMP	MGI:MGI:5295267	Mouse	PMID:24360193
Biological Process	GO:0060541	respiratory system development	Spef2	IMP	MGI:MGI:5295267	Mouse	PMID:21715716
Biological Process	GO:0048705	skeletal system morphogenesis	Spef2	IMP	MGI:MGI:5295267	Mouse	PMID:21715716
Biological Process	GO:0007288	sperm axoneme assembly	SPEF2	IMP		Human	PMID:31048344
Biological Process	GO:0007288	sperm axoneme assembly	SPEF2	IMP		Human	PMID:31151990
Biological Process	GO:0007288	sperm axoneme assembly	Spef2	IMP	MGI:MGI:5295267	Mouse	PMID:21715716
Biological Process	GO:0120316	sperm flagellum assembly	Spef2	IGI	MGI:MGI:1922208	Mouse	PMID:32704025
Biological Process	GO:0007283	spermatogenesis	Spef2	IMP	MGI:MGI:5295267	Mouse	PMID:21715716

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern