Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPC25
  • Mouse genes Spc25
  • Rat genes Spc25
  • Zfish genes spc25
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Spc25

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SPC25	IPI	UniProtKB:O14777	Human	PMID:14699129
Molecular Function	GO:0005515	protein binding	SPC25	IPI	UniProtKB:Q8NBT2	Human	PMID:14738735
Molecular Function	GO:0005515	protein binding	SPC25	IPI	UniProtKB:O14777	Human	PMID:15961401
Molecular Function	GO:0005515	protein binding	SPC25	IPI	UniProtKB:Q8NBT2	Human	PMID:15961401
Molecular Function	GO:0005515	protein binding	SPC25	IPI	UniProtKB:O14777	Human	PMID:20360068
Molecular Function	GO:0005515	protein binding	SPC25	IPI	UniProtKB:O14777	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	SPC25	IPI	UniProtKB:O14777	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPC25	IPI	UniProtKB:Q8NBT2	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	SPC25	IPI	UniProtKB:O14777	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	SPC25	IPI	UniProtKB:Q8NBT2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	SPC25	IPI	UniProtKB:O14964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPC25	IPI	UniProtKB:Q8NBT2	Human	PMID:32296183
Cellular Component	GO:0005829	cytosol	SPC25	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000776	kinetochore	SPC25	IDA		Human	PMID:14699129
Cellular Component	GO:0000776	kinetochore	SPC25	IDA		Human	PMID:15961401
Cellular Component	GO:0031262	Ndc80 complex	SPC25	IPI		Human	PMID:18455984
Cellular Component	GO:0031262	Ndc80 complex	SPC25	IDA		Human	PMID:14699129
Biological Process	GO:0008608	attachment of spindle microtubules to kinetochore	SPC25	IDA		Human	PMID:18455984
Biological Process	GO:0007059	chromosome segregation	SPC25	IMP		Human	PMID:14699129
Biological Process	GO:0007052	mitotic spindle organization	SPC25	IMP		Human	PMID:14699129

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern