Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SMG5
  • Mouse genes Smg5
  • Rat genes Smg5
  • Zfish genes smg5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Smg5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042826	histone deacetylase binding	SMG5	IPI	UniProtKB:Q9BY41	Human	PMID:16809764
Molecular Function	GO:0005515	protein binding	SMG5	IPI	UniProtKB:O14746	Human	PMID:12699629
Molecular Function	GO:0005515	protein binding	SMG5	IPI	UniProtKB:Q92540	Human	PMID:14636577
Molecular Function	GO:0005515	protein binding	SMG5	IPI	UniProtKB:Q92900	Human	PMID:14636577
Molecular Function	GO:0005515	protein binding	SMG5	IPI	UniProtKB:Q86US8	Human	PMID:20930030
Molecular Function	GO:0005515	protein binding	SMG5	IPI	UniProtKB:Q92900-2	Human	PMID:21145460
Molecular Function	GO:0005515	protein binding	SMG5	IPI	UniProtKB:Q92540	Human	PMID:23348841
Molecular Function	GO:0051721	protein phosphatase 2A binding	SMG5	IDA		Human	PMID:14636577
Molecular Function	GO:0070034	telomerase RNA binding	SMG5	IPI	RNAcentral:URS00004416C5_9606	Human	PMID:15857955
Molecular Function	GO:0070034	telomerase RNA binding	SMG5	IPI	RNAcentral:URS00004A7003_9606	Human	PMID:15857955
Molecular Function	GO:0042162	telomeric DNA binding	SMG5	IDA		Human	PMID:17916692
Molecular Function	GO:0031625	ubiquitin protein ligase binding	SMG5	IPI	UniProtKB:Q9UNE7	Human	PMID:16809764
Cellular Component	GO:0005737	cytoplasm	SMG5	IDA		Human	PMID:14636577
Cellular Component	GO:0005634	nucleus	SMG5	IDA		Human	PMID:14636577
Biological Process	GO:0043009	chordate embryonic development	smg5	IMP	ZFIN:ZDB-MRPHLNO-090715-5	Zfish	PMID:19414594
Biological Process	GO:0035303	regulation of dephosphorylation	SMG5	IMP		Human	PMID:14636577
Biological Process	GO:0032204	regulation of telomere maintenance	SMG5	IMP		Human	PMID:16809764

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern