Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SMARCA1
  • Mouse genes Smarca1
  • Rat genes Smarca1
  • Zfish genes smarca1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Smarca1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008094	ATP-dependent activity, acting on DNA	SMARCA1	IDA		Human	PMID:14609955
Molecular Function	GO:0140658	ATP-dependent chromatin remodeler activity	SMARCA1	IDA		Human	PMID:15640247
Molecular Function	GO:0036310	ATP-dependent DNA/DNA annealing activity	SMARCA1	IDA		Human	PMID:22705370
Molecular Function	GO:0003682	chromatin binding	Smarca1	IDA		Mouse	PMID:22516202
Molecular Function	GO:0005515	protein binding	SMARCA1	IPI	UniProtKB:Q09028	Human	PMID:14609955
Molecular Function	GO:0005515	protein binding	SMARCA1	IPI	UniProtKB:Q12830	Human	PMID:14609955
Molecular Function	GO:0005515	protein binding	SMARCA1	IPI	UniProtKB:Q12830	Human	PMID:15640247
Molecular Function	GO:0005515	protein binding	SMARCA1	IPI	UniProtKB:Q03468	Human	PMID:26030138
Molecular Function	GO:0005515	protein binding	smarca1	IPI	ZFIN:ZDB-GENE-030131-3200	Zfish	PMID:26041917
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	SMARCA1	IPI	UniProtKB:P22415	Human	PMID:27141965
Cellular Component	GO:1904949	ATPase complex	SMARCA1	IDA		Human	PMID:14609955
Cellular Component	GO:0090537	CERF complex	SMARCA1	IPI		Human	PMID:15640247
Cellular Component	GO:0090537	CERF complex	SMARCA1	IDA		Human	PMID:15640247
Cellular Component	GO:0000785	chromatin	Smarca1	IDA		Mouse	PMID:22516202
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	SMARCA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SMARCA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SMARCA1	IDA		Human	PMID:14609955
Cellular Component	GO:0005634	nucleus	Smarca1	IDA		Mouse	PMID:22516202
Cellular Component	GO:0016589	NURF complex	SMARCA1	IPI		Human	PMID:14609955
Cellular Component	GO:0016589	NURF complex	SMARCA1	IDA		Human	PMID:20850016
Biological Process	GO:0007420	brain development	SMARCA1	IMP		Human	PMID:14609955
Biological Process	GO:0007420	brain development	Smarca1	IMP	MGI:MGI:5427348	Mouse	PMID:22516202
Biological Process	GO:0006338	chromatin remodeling	SMARCA1	IDA		Human	PMID:14609955
Biological Process	GO:0006338	chromatin remodeling	SMARCA1	IDA		Human	PMID:15640247
Biological Process	GO:0021999	neural plate anterior/posterior regionalization	smarca1	IGI	ZFIN:ZDB-GENE-030131-3200	Zfish	PMID:26041917
Biological Process	GO:0030182	neuron differentiation	Smarca1	IMP		Mouse	MGI:MGI:3690152|PMID:14609955
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	SMARCA1	IMP		Human	PMID:14609955
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	SMARCA1	IMP		Human	PMID:14609955
Biological Process	GO:0060319	primitive erythrocyte differentiation	smarca1	IMP	ZFIN:ZDB-MRPHLNO-141210-6	Zfish	PMID:24240475
Biological Process	GO:0060215	primitive hemopoiesis	smarca1	IMP	ZFIN:ZDB-MRPHLNO-141210-6	Zfish	PMID:24240475
Biological Process	GO:0006355	regulation of DNA-templated transcription	SMARCA1	IDA		Human	PMID:14609955
Biological Process	GO:2000177	regulation of neural precursor cell proliferation	Smarca1	IGI	MGI:MGI:1347464	Mouse	PMID:22516202
Biological Process	GO:2000177	regulation of neural precursor cell proliferation	Smarca1	IMP	MGI:MGI:5427348	Mouse	PMID:22516202

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern