Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLX1A,SLX1B
  • Mouse genes Slx1b
  • Rat genes Slx1b
  • Zfish genes slx1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slx1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0017108	5'-flap endonuclease activity	SLX1A	IDA		Human	PMID:19596235
Molecular Function	GO:0017108	5'-flap endonuclease activity	SLX1A	IDA		Human	PMID:19596236
Molecular Function	GO:0008821	crossover junction DNA endonuclease activity	SLX1A	IDA		Human	PMID:19595721
Molecular Function	GO:0008821	crossover junction DNA endonuclease activity	SLX1A	IDA		Human	PMID:19596235
Molecular Function	GO:0008821	crossover junction DNA endonuclease activity	SLX1A	IDA		Human	PMID:19596236
Molecular Function	GO:0005515	protein binding	SLX1A	IPI	UniProtKB:Q8IY92	Human	PMID:19595721
Molecular Function	GO:0005515	protein binding	SLX1A	IPI	UniProtKB:Q8IY92	Human	PMID:19596235
Molecular Function	GO:0005515	protein binding	SLX1A	IPI	UniProtKB:Q8IY92	Human	PMID:19596236
Cellular Component	GO:0005654	nucleoplasm	SLX1A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0033557	Slx1-Slx4 complex	SLX1A	IDA		Human	PMID:19595721
Cellular Component	GO:0033557	Slx1-Slx4 complex	SLX1A	IDA		Human	PMID:19596235
Cellular Component	GO:0033557	Slx1-Slx4 complex	SLX1A	IDA		Human	PMID:19596236
Biological Process	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing	SLX1A	IMP		Human	PMID:19595721
Biological Process	GO:0006281	DNA repair	SLX1A	IMP		Human	PMID:19595721
Biological Process	GO:0006281	DNA repair	SLX1A	IMP		Human	PMID:19595722
Biological Process	GO:0006281	DNA repair	SLX1A	IMP		Human	PMID:19596235
Biological Process	GO:0006281	DNA repair	SLX1A	IMP		Human	PMID:19596236
Biological Process	GO:0000724	double-strand break repair via homologous recombination	SLX1A	IMP		Human	PMID:19595721
Biological Process	GO:1904357	negative regulation of telomere maintenance via telomere lengthening	SLX1A	IMP		Human	PMID:24012755
Biological Process	GO:1904431	positive regulation of t-circle formation	Slx1b	IMP		Mouse	MGI:MGI:5645200|PMID:22579284
Biological Process	GO:0090656	t-circle formation	SLX1A	IMP		Human	PMID:24012755
Biological Process	GO:0090656	t-circle formation	Slx1b	IMP		Mouse	MGI:MGI:5645200|PMID:22579284
Biological Process	GO:0010833	telomere maintenance via telomere lengthening	SLX1A	IMP		Human	PMID:24012755
Biological Process	GO:0061820	telomeric D-loop disassembly	SLX1A	IMP		Human	PMID:24012755

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern