Comparative GO Graph (mouse, human)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLFN14
  • Mouse genes Slfn14
  • Rat genes
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slfn14

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043022	ribosome binding	SLFN14	IDA		Human	PMID:25996083
Molecular Function	GO:0043022	ribosome binding	Slfn14	IDA		Mouse	MGI:MGI:5705207|PMID:25996083
Molecular Function	GO:0004521	RNA endonuclease activity	SLFN14	IDA		Human	PMID:25996083
Molecular Function	GO:0004521	RNA endonuclease activity	Slfn14	IDA		Mouse	MGI:MGI:5705207|PMID:25996083
Cellular Component	GO:0005737	cytoplasm	SLFN14	IDA		Human	PMID:26280575
Cellular Component	GO:0005634	nucleus	SLFN14	IDA		Human	PMID:25996083
Cellular Component	GO:0005634	nucleus	SLFN14	IDA		Human	PMID:26280575
Cellular Component	GO:0005634	nucleus	Slfn14	IDA		Mouse	MGI:MGI:5705207|PMID:25996083
Biological Process	GO:0006402	mRNA catabolic process	SLFN14	IDA		Human	PMID:25996083
Biological Process	GO:0006402	mRNA catabolic process	Slfn14	IDA		Mouse	MGI:MGI:5705207|PMID:25996083
Biological Process	GO:0036345	platelet maturation	SLFN14	IMP		Human	PMID:26769223
Biological Process	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	SLFN14	IDA		Human	PMID:25996083
Biological Process	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	Slfn14	IDA		Mouse	MGI:MGI:5705207|PMID:25996083
Biological Process	GO:0016075	rRNA catabolic process	SLFN14	IDA		Human	PMID:25996083
Biological Process	GO:0016075	rRNA catabolic process	Slfn14	IDA		Mouse	MGI:MGI:5705207|PMID:25996083

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern