Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC5A6
  • Mouse genes Slc5a6
  • Rat genes Slc5a6
  • Zfish genes slc5a6a,slc5a6b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc5a6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015225	biotin transmembrane transporter activity	SLC5A6	IMP		Human	PMID:15561972
Molecular Function	GO:0015225	biotin transmembrane transporter activity	SLC5A6	IDA		Human	PMID:21570947
Molecular Function	GO:0015225	biotin transmembrane transporter activity	SLC5A6	IDA		Human	PMID:22015582
Molecular Function	GO:0015225	biotin transmembrane transporter activity	SLC5A6	IMP		Human	PMID:25809983
Molecular Function	GO:0015233	pantothenate transmembrane transporter activity	SLC5A6	IMP		Human	PMID:25809983
Molecular Function	GO:0005515	protein binding	SLC5A6	IPI	UniProtKB:Q5EBL8	Human	PMID:21183659
Molecular Function	GO:0008523	sodium-dependent multivitamin transmembrane transporter activity	Slc5a6	IDA		Rat	PMID:9516450|RGD:68917
Molecular Function	GO:0090482	vitamin transmembrane transporter activity	SLC5A6	IDA		Human	PMID:25971966
Cellular Component	GO:0031526	brush border membrane	Slc5a6	IDA		Rat	PMID:12620923|RGD:730078
Cellular Component	GO:0005886	plasma membrane	SLC5A6	IDA		Human	PMID:27904971
Cellular Component	GO:0005886	plasma membrane	SLC5A6	IDA		Human	PMID:28052864
Cellular Component	GO:0005886	plasma membrane	SLC5A6	IDA		Human	PMID:25809983
Cellular Component	GO:0012506	vesicle membrane	Slc5a6	IDA		Rat	PMID:12620923|RGD:730078
Biological Process	GO:1905135	biotin import across plasma membrane	SLC5A6	IMP		Human	PMID:15561972
Biological Process	GO:1905135	biotin import across plasma membrane	SLC5A6	IDA		Human	PMID:21570947
Biological Process	GO:1905135	biotin import across plasma membrane	SLC5A6	IDA		Human	PMID:22015582
Biological Process	GO:1905135	biotin import across plasma membrane	SLC5A6	IMP		Human	PMID:25809983
Biological Process	GO:0015878	biotin transport	Slc5a6	IDA		Rat	PMID:9516450|RGD:68917
Biological Process	GO:1904200	iodide transmembrane transport	SLC5A6	IDA		Human	PMID:20980265
Biological Process	GO:0015887	pantothenate transmembrane transport	SLC5A6	IMP		Human	PMID:25809983
Biological Process	GO:0015887	pantothenate transmembrane transport	Slc5a6	IDA		Rat	PMID:9516450|RGD:68917
Biological Process	GO:0150104	transport across blood-brain barrier	SLC5A6	IMP		Human	PMID:25809983

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern