Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC47A1,SLC47A2
  • Mouse genes Slc47a2
  • Rat genes Slc47a2
  • Zfish genes slc47a2.1,slc47a2.2,slc47a3,slc47a4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc47a2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015297	antiporter activity	SLC47A2	IDA		Human	PMID:16807400
Molecular Function	GO:0015297	antiporter activity	SLC47A1	IDA		Human	PMID:16330770
Molecular Function	GO:0015297	antiporter activity	SLC47A1	IDA		Human	PMID:17509534
Molecular Function	GO:0015179	L-amino acid transmembrane transporter activity	SLC47A1	IMP		Human	PMID:23864433
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	SLC47A1	IMP		Human	PMID:23864433
Molecular Function	GO:0015101	organic cation transmembrane transporter activity	SLC47A2	IDA		Human	PMID:16807400
Molecular Function	GO:0015101	organic cation transmembrane transporter activity	SLC47A1	IDA		Human	PMID:16330770
Molecular Function	GO:0015101	organic cation transmembrane transporter activity	SLC47A1	IDA		Human	PMID:17509534
Molecular Function	GO:0015101	organic cation transmembrane transporter activity	SLC47A1	IDA		Human	PMID:21128598
Molecular Function	GO:0015101	organic cation transmembrane transporter activity	Slc47a2	IDA		Mouse	MGI:MGI:6708635|PMID:17715386
Molecular Function	GO:0140968	polyspecific organic cation:proton antiporter activity	SLC47A2	IDA		Human	PMID:16807400
Molecular Function	GO:0140968	polyspecific organic cation:proton antiporter activity	SLC47A1	IDA		Human	PMID:16330770
Molecular Function	GO:0140968	polyspecific organic cation:proton antiporter activity	SLC47A1	IDA		Human	PMID:17509534
Molecular Function	GO:0140968	polyspecific organic cation:proton antiporter activity	Slc47a2	IDA		Mouse	MGI:MGI:6708635|PMID:17715386
Molecular Function	GO:0005515	protein binding	SLC47A1	IPI	UniProtKB:Q9H0Q3	Human	PMID:32296183
Molecular Function	GO:0015489	putrescine transmembrane transporter activity	SLC47A1	IDA		Human	PMID:21128598
Molecular Function	GO:0015234	thiamine transmembrane transporter activity	SLC47A1	IDA		Human	PMID:24961373
Molecular Function	GO:0042910	xenobiotic transmembrane transporter activity	SLC47A1	IDA		Human	PMID:16330770
Molecular Function	GO:0042910	xenobiotic transmembrane transporter activity	SLC47A1	IDA		Human	PMID:17509534
Cellular Component	GO:0016324	apical plasma membrane	SLC47A1	IDA		Human	PMID:16330770
Cellular Component	GO:0016324	apical plasma membrane	SLC47A1	IDA		Human	PMID:31791063
Cellular Component	GO:0016323	basolateral plasma membrane	SLC47A1	IDA		Human	PMID:31791063
Cellular Component	GO:0005886	plasma membrane	SLC47A2	IDA		Human	PMID:19158817
Cellular Component	GO:0005886	plasma membrane	SLC47A1	IDA		Human	PMID:28112518
Cellular Component	GO:0005886	plasma membrane	Slc47a2	IDA		Mouse	MGI:MGI:6708635|PMID:17715386
Biological Process	GO:0089718	amino acid import across plasma membrane	SLC47A1	IMP		Human	PMID:23864433
Biological Process	GO:1902475	L-alpha-amino acid transmembrane transport	SLC47A1	IMP		Human	PMID:23864433
Biological Process	GO:0097638	L-arginine import across plasma membrane	SLC47A1	IMP		Human	PMID:23864433
Biological Process	GO:0015695	organic cation transport	SLC47A2	IDA		Human	PMID:16807400
Biological Process	GO:0015695	organic cation transport	SLC47A1	IDA		Human	PMID:16330770
Biological Process	GO:0015695	organic cation transport	SLC47A1	IDA		Human	PMID:17509534
Biological Process	GO:0015695	organic cation transport	Slc47a2	IDA		Mouse	MGI:MGI:6708635|PMID:17715386
Biological Process	GO:0015847	putrescine transport	SLC47A1	IDA		Human	PMID:21128598
Biological Process	GO:1990961	xenobiotic detoxification by transmembrane export across the plasma membrane	SLC47A1	IDA		Human	PMID:16330770
Biological Process	GO:0042908	xenobiotic transport	SLC47A1	IMP		Human	PMID:23864433

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern