Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC3A1
  • Mouse genes Slc3a1
  • Rat genes Slc3a1
  • Zfish genes slc3a1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc3a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SLC3A1	IPI	UniProtKB:P82251	Human	PMID:12167606
Molecular Function	GO:0005515	protein binding	SLC3A1	IPI	UniProtKB:P82251	Human	PMID:32494597
Molecular Function	GO:0005515	protein binding	Slc3a1	IPI	UniProtKB:Q9QXA6	Mouse	MGI:MGI:5546001|PMID:12167606
Molecular Function	GO:0005515	protein binding	Slc3a1	IPI	UniProtKB:Q91WN3	Mouse	PMID:26739563
Molecular Function	GO:0005515	protein binding	Slc3a1	IPI	MGI:MGI:3045351	Mouse	PMID:15757906
Molecular Function	GO:0046982	protein heterodimerization activity	SLC3A1	IDA		Human	PMID:32494597
Molecular Function	GO:0046982	protein heterodimerization activity	Slc3a1	IPI	UniProtKB:Q91WN3	Mouse	PMID:26739563
Molecular Function	GO:0044877	protein-containing complex binding	Slc3a1	IDA		Rat	PMID:7628645|RGD:1600022
Cellular Component	GO:0016324	apical plasma membrane	Slc3a1	IPI	UniProtKB:Q91WN3	Mouse	PMID:26739563
Cellular Component	GO:0031526	brush border membrane	SLC3A1	IDA		Human	PMID:12167606
Cellular Component	GO:0031526	brush border membrane	Slc3a1	IDA		Mouse	MGI:MGI:5546001|PMID:12167606
Cellular Component	GO:0070062	extracellular exosome	SLC3A1	HDA		Human	PMID:19056867
Cellular Component	GO:0005743	mitochondrial inner membrane	Slc3a1	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005886	plasma membrane	Slc3a1	IDA		Rat	PMID:7926373|RGD:1600023
Cellular Component	GO:0005886	plasma membrane	Slc3a1	IDA		Rat	PMID:9987991|RGD:1600019
Cellular Component	GO:0005774	vacuolar membrane	Slc3a1	IDA		Rat	PMID:9987991|RGD:1600019
Biological Process	GO:0006865	amino acid transport	Slc3a1	IDA		Rat	PMID:1376924|RGD:70013
Biological Process	GO:0015810	aspartate transmembrane transport	Slc3a1	IDA		Mouse	PMID:26739563
Biological Process	GO:0010467	gene expression	Slc3a1	IMP	MGI:MGI:2677291	Mouse	PMID:26739563
Biological Process	GO:0015811	L-cystine transport	Slc3a1	IDA		Mouse	PMID:26739563
Biological Process	GO:0015813	L-glutamate transmembrane transport	Slc3a1	IDA		Mouse	PMID:26739563

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern