Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC16A12
  • Mouse genes Slc16a12
  • Rat genes Slc16a12
  • Zfish genes slc16a12a,slc16a12b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc16a12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005308	creatine transmembrane transporter activity	SLC16A12	IDA		Human	PMID:23578822
Molecular Function	GO:0005308	creatine transmembrane transporter activity	SLC16A12	IDA		Human	PMID:29088427
Molecular Function	GO:0005308	creatine transmembrane transporter activity	SLC16A12	IDA		Human	PMID:31784090
Molecular Function	GO:0005308	creatine transmembrane transporter activity	Slc16a12	IDA		Rat	PMID:34075817|RGD:153298943
Molecular Function	GO:0005515	protein binding	SLC16A12	IPI	UniProtKB:P11912	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC16A12	IPI	UniProtKB:P48165	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC16A12	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC16A12	IPI	UniProtKB:Q14802-3	Human	PMID:32296183
Molecular Function	GO:0015292	uniporter activity	SLC16A12	IDA		Human	PMID:32249133
Cellular Component	GO:0016323	basolateral plasma membrane	Slc16a12	IDA		Mouse	MGI:MGI:6436443|PMID:26376857
Cellular Component	GO:0016323	basolateral plasma membrane	Slc16a12	IDA		Rat	PMID:34075817|RGD:153298943
Cellular Component	GO:0005886	plasma membrane	SLC16A12	IDA		Human	PMID:21778275
Cellular Component	GO:0005886	plasma membrane	SLC16A12	IDA		Human	PMID:23578822
Cellular Component	GO:0005886	plasma membrane	SLC16A12	IDA		Human	PMID:31784090
Cellular Component	GO:0005886	plasma membrane	SLC16A12	IDA		Human	PMID:29088427
Biological Process	GO:0015881	creatine transmembrane transport	SLC16A12	IDA		Human	PMID:23578822
Biological Process	GO:0015881	creatine transmembrane transport	SLC16A12	IDA		Human	PMID:29088427
Biological Process	GO:0015881	creatine transmembrane transport	SLC16A12	IDA		Human	PMID:31784090
Biological Process	GO:0015881	creatine transmembrane transport	Slc16a12	IDA		Rat	PMID:34075817|RGD:153298943
Biological Process	GO:0046449	creatinine metabolic process	Slc16a12	IDA		Rat	PMID:34075817|RGD:153298943

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern