Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SIKE1
  • Mouse genes Sike1
  • Rat genes Sike1
  • Zfish genes sike1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sike1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SIKE1	IPI	UniProtKB:Q9Y228	Human	PMID:18782753
Molecular Function	GO:0005515	protein binding	SIKE1	IPI	UniProtKB:Q13033-2	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	SIKE1	IPI	UniProtKB:O43439-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SIKE1	IPI	UniProtKB:O75558	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SIKE1	IPI	UniProtKB:P40222	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SIKE1	IPI	UniProtKB:P78358	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SIKE1	IPI	UniProtKB:Q13033-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SIKE1	IPI	UniProtKB:Q53FD0-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SIKE1	IPI	UniProtKB:Q7L2Z9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SIKE1	IPI	UniProtKB:Q8N3L3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SIKE1	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SIKE1	IPI	UniProtKB:Q9UIL1-3	Human	PMID:32296183
Molecular Function	GO:0019901	protein kinase binding	SIKE1	IPI	UniProtKB:Q9Y5S2	Human	PMID:25743393
Molecular Function	GO:0031267	small GTPase binding	SIKE1	IPI	UniProtKB:B7Z964,UniProtKB:Q13033,UniProtKB:Q86XZ8,UniProtKB:Q8C079,UniProtKB:Q9UPN7	Human	PMID:25743393

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern