Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SHISA5
  • Mouse genes Shisa5
  • Rat genes Shisa5
  • Zfish genes shisa10.1,shisa10.2,shisa10.4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Shisa5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SHISA5	IPI	UniProtKB:Q9NZC7	Human	PMID:15064722
Molecular Function	GO:0005515	protein binding	SHISA5	IPI	UniProtKB:P12815	Human	PMID:17889823
Cellular Component	GO:0005783	endoplasmic reticulum	Shisa5	IDA		Mouse	PMID:12135983
Cellular Component	GO:0005635	nuclear envelope	Shisa5	IDA		Mouse	PMID:12135983
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	Shisa5	IMP		Mouse	PMID:12135983
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Shisa5	IDA		Mouse	PMID:12135983
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	SHISA5	HMP		Human	PMID:12761501

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern