Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SH3PXD2B
  • Mouse genes Sh3pxd2b
  • Rat genes Sh3pxd2b
  • Zfish genes sh3pxd2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sh3pxd2b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	Sh3pxd2b	IDA		Mouse	MGI:MGI:3826299|PMID:18959745
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	Sh3pxd2b	IMP		Mouse	MGI:MGI:3826299|PMID:18959745
Molecular Function	GO:0070273	phosphatidylinositol-4-phosphate binding	Sh3pxd2b	IDA		Mouse	MGI:MGI:3826299|PMID:18959745
Molecular Function	GO:0010314	phosphatidylinositol-5-phosphate binding	Sh3pxd2b	IDA		Mouse	MGI:MGI:3826299|PMID:18959745
Molecular Function	GO:0005515	protein binding	SH3PXD2B	IPI	UniProtKB:Q86UR1	Human	PMID:19755710
Molecular Function	GO:0005515	protein binding	SH3PXD2B	IPI	UniProtKB:Q86UR1	Human	PMID:20609497
Molecular Function	GO:0042169	SH2 domain binding	Sh3pxd2b	IDA		Mouse	MGI:MGI:3826299|PMID:18959745
Cellular Component	GO:0005737	cytoplasm	Sh3pxd2b	IDA		Mouse	MGI:MGI:4943661|PMID:19144821
Cellular Component	GO:0005737	cytoplasm	Sh3pxd2b	IDA		Mouse	MGI:MGI:3826299|PMID:18959745
Cellular Component	GO:0005737	cytoplasm	Sh3pxd2b	IDA		Mouse	MGI:MGI:4365313|PMID:19669234
Cellular Component	GO:0005737	cytoplasm	Sh3pxd2b	IDA		Mouse	MGI:MGI:5800302|PMID:27711054
Cellular Component	GO:0002102	podosome	Sh3pxd2b	IDA		Mouse	MGI:MGI:4365313|PMID:19669234
Cellular Component	GO:0002102	podosome	Sh3pxd2b	IDA		Mouse	MGI:MGI:4943661|PMID:19144821
Biological Process	GO:0060612	adipose tissue development	Sh3pxd2b	IMP		Mouse	MGI:MGI:4439252|PMID:20137777
Biological Process	GO:0060348	bone development	SH3PXD2B	IMP		Human	PMID:20137777
Biological Process	GO:0060348	bone development	Sh3pxd2b	IMP		Mouse	MGI:MGI:4439252|PMID:20137777
Biological Process	GO:0060349	bone morphogenesis	sh3pxd2b	IMP	ZFIN:ZDB-GENO-220523-2	Zfish	PMID:33234702
Biological Process	GO:0061448	connective tissue development	sh3pxd2b	IMP	ZFIN:ZDB-GENO-220523-2	Zfish	PMID:33234702
Biological Process	GO:1904888	cranial skeletal system development	Sh3pxd2b	IMP		Mouse	MGI:MGI:5800302|PMID:27711054
Biological Process	GO:0022617	extracellular matrix disassembly	SH3PXD2B	IMP		Human	PMID:19755710
Biological Process	GO:0001654	eye development	SH3PXD2B	IMP		Human	PMID:20137777
Biological Process	GO:0001654	eye development	Sh3pxd2b	IMP		Mouse	MGI:MGI:4439252|PMID:20137777
Biological Process	GO:0007507	heart development	SH3PXD2B	IMP		Human	PMID:20137777
Biological Process	GO:0007507	heart development	Sh3pxd2b	IMP		Mouse	MGI:MGI:4439252|PMID:20137777
Biological Process	GO:0002051	osteoblast fate commitment	Sh3pxd2b	IMP		Mouse	MGI:MGI:5800302|PMID:27711054
Biological Process	GO:0071800	podosome assembly	Sh3pxd2b	IMP		Mouse	MGI:MGI:4943661|PMID:19144821
Biological Process	GO:1904179	positive regulation of adipose tissue development	Sh3pxd2b	IMP		Mouse	MGI:MGI:5800302|PMID:27711054
Biological Process	GO:0045600	positive regulation of fat cell differentiation	Sh3pxd2b	IMP		Mouse	MGI:MGI:3826299|PMID:18959745
Biological Process	GO:0045600	positive regulation of fat cell differentiation	Sh3pxd2b	IMP		Mouse	MGI:MGI:5800302|PMID:27711054
Biological Process	GO:0010628	positive regulation of gene expression	Sh3pxd2b	IMP		Mouse	MGI:MGI:5800302|PMID:27711054
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Sh3pxd2b	IMP		Mouse	MGI:MGI:5800302|PMID:27711054
Biological Process	GO:0051496	positive regulation of stress fiber assembly	Sh3pxd2b	IMP		Mouse	MGI:MGI:5800302|PMID:27711054
Biological Process	GO:0072657	protein localization to membrane	SH3PXD2B	IDA		Human	PMID:19755710
Biological Process	GO:0060378	regulation of brood size	Sh3pxd2b	IMP		Mouse	MGI:MGI:5800302|PMID:27711054
Biological Process	GO:0001501	skeletal system development	SH3PXD2B	IMP		Human	PMID:20137777
Biological Process	GO:0001501	skeletal system development	Sh3pxd2b	IMP		Mouse	MGI:MGI:4439252|PMID:20137777
Biological Process	GO:0048705	skeletal system morphogenesis	Sh3pxd2b	IMP		Mouse	MGI:MGI:5800302|PMID:27711054
Biological Process	GO:0006801	superoxide metabolic process	SH3PXD2B	IDA		Human	PMID:19755710

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern