Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SETDB2
  • Mouse genes Setdb2
  • Rat genes Setdb2
  • Zfish genes setdb2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Setdb2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	SETDB2	IDA		Human	PMID:20404330
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	setdb2	IMP	ZFIN:ZDB-MRPHLNO-110201-1	Zfish	PMID:20133783
Molecular Function	GO:0005515	protein binding	SETDB2	IPI	UniProtKB:Q8N8R7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SETDB2	IPI	UniProtKB:Q8N8R7	Human	PMID:31515488
Cellular Component	GO:0005829	cytosol	SETDB2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SETDB2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SETDB2	IDA		Human	PMID:20404330
Biological Process	GO:0007059	chromosome segregation	SETDB2	IMP		Human	PMID:20404330
Biological Process	GO:0060027	convergent extension involved in gastrulation	setdb2	IMP	ZFIN:ZDB-MRPHLNO-110201-1	Zfish	PMID:24892953
Biological Process	GO:0060027	convergent extension involved in gastrulation	setdb2	IGI	ZFIN:ZDB-GENE-980526-389	Zfish	PMID:24892953
Biological Process	GO:0007368	determination of left/right symmetry	setdb2	IMP	ZFIN:ZDB-MRPHLNO-110201-2	Zfish	PMID:20133783
Biological Process	GO:0007368	determination of left/right symmetry	setdb2	IMP	ZFIN:ZDB-MRPHLNO-110201-1	Zfish	PMID:20133783
Biological Process	GO:0001947	heart looping	setdb2	IMP		Zfish	PMID:20133783|ZFIN:ZDB-PUB-110128-11
Biological Process	GO:0051567	histone H3-K9 methylation	setdb2	IMP		Zfish	PMID:20133783|ZFIN:ZDB-PUB-110128-11
Biological Process	GO:0070986	left/right axis specification	setdb2	IMP		Zfish	PMID:20133783|ZFIN:ZDB-PUB-110128-11
Biological Process	GO:0000278	mitotic cell cycle	SETDB2	IMP		Human	PMID:20404330
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	setdb2	IMP		Zfish	PMID:20133783|ZFIN:ZDB-PUB-110128-11

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern