Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RUFY1
  • Mouse genes Rufy1
  • Rat genes Rufy1
  • Zfish genes rufy1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rufy1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RUFY1	IPI	UniProtKB:O75928	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	RUFY1	IPI	UniProtKB:Q68CQ4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RUFY1	IPI	UniProtKB:Q96DA2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RUFY1	IPI	UniProtKB:Q96QF0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RUFY1	IPI	UniProtKB:Q9BRA2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RUFY1	IPI	UniProtKB:Q68CQ4	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	RUFY1	IPI	UniProtKB:Q68CQ4	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	RUFY1	IPI	UniProtKB:Q96DA2	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Rufy1	IPI	PR:P56371	Mouse	PMID:11172003
Molecular Function	GO:0042169	SH2 domain binding	RUFY1	IPI	UniProtKB:P29320	Human	PMID:11877430
Molecular Function	GO:0017124	SH3 domain binding	RUFY1	IPI	UniProtKB:P29320	Human	PMID:11877430
Cellular Component	GO:0005737	cytoplasm	Rufy1	IDA		Mouse	PMID:11172003
Cellular Component	GO:0005829	cytosol	RUFY1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005768	endosome	RUFY1	IDA		Human	PMID:11877430
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	RUFY1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	RUFY1	IDA		Human	GO_REF:0000052
Biological Process	GO:0015031	protein transport	Rufy1	IDA		Mouse	PMID:11172003
Biological Process	GO:0030100	regulation of endocytosis	RUFY1	IPI	UniProtKB:P29320	Human	PMID:11877430
Biological Process	GO:0030100	regulation of endocytosis	Rufy1	IDA		Mouse	PMID:11172003
Biological Process	GO:0007264	small GTPase mediated signal transduction	Rufy1	IDA		Mouse	PMID:11172003

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern