Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RIOX1
  • Mouse genes Riox1
  • Rat genes Riox1
  • Zfish genes riox1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Riox1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016706	2-oxoglutarate-dependent dioxygenase activity	RIOX1	IDA		Human	PMID:35210392
Molecular Function	GO:0016706	2-oxoglutarate-dependent dioxygenase activity	Riox1	IMP		Mouse	MGI:MGI:4418587|PMID:19927124
Molecular Function	GO:0016706	2-oxoglutarate-dependent dioxygenase activity	Riox1	IDA		Mouse	PMID:35210392
Molecular Function	GO:0051864	histone H3K36 demethylase activity	Riox1	IDA		Mouse	MGI:MGI:4418587|PMID:19927124
Molecular Function	GO:0034647	histone H3K4me/H3K4me2/H3K4me3 demethylase activity	Riox1	IDA		Mouse	MGI:MGI:4418587|PMID:19927124
Molecular Function	GO:0005506	iron ion binding	Riox1	IMP		Mouse	MGI:MGI:4418587|PMID:19927124
Molecular Function	GO:0036139	peptidyl-histidine dioxygenase activity	RIOX1	IDA		Human	PMID:23103944
Molecular Function	GO:0005515	protein binding	RIOX1	IPI	UniProtKB:Q8VI67	Human	PMID:19927124
Molecular Function	GO:0005515	protein binding	RIOX1	IPI	UniProtKB:Q5T6S3	Human	PMID:23160351
Molecular Function	GO:0005515	protein binding	Riox1	IPI	UniProtKB:Q8VI67	Mouse	MGI:MGI:4418587|PMID:19927124
Molecular Function	GO:0140457	protein demethylase activity	RIOX1	IDA		Human	PMID:35210392
Molecular Function	GO:0140457	protein demethylase activity	Riox1	IDA		Mouse	MGI:MGI:7294462|PMID:35210392
Cellular Component	GO:0005730	nucleolus	RIOX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	Riox1	IDA		Mouse	PMID:14742713
Cellular Component	GO:0005634	nucleus	Riox1	IDA		Mouse	MGI:MGI:4418587|PMID:19927124
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Riox1	IDA		Mouse	MGI:MGI:4418587|PMID:19927124
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	Riox1	IMP		Mouse	MGI:MGI:4418587|PMID:19927124
Biological Process	GO:0006482	protein demethylation	Riox1	IDA		Mouse	PMID:35210392

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern