Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RIOK3
  • Mouse genes Riok3
  • Rat genes Riok3
  • Zfish genes riok3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Riok3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0089720	caspase binding	RIOK3	IDA		Human	PMID:19557502
Molecular Function	GO:0005515	protein binding	RIOK3	IPI	UniProtKB:Q92851	Human	PMID:19557502
Molecular Function	GO:0005515	protein binding	RIOK3	IPI	UniProtKB:Q92851-7	Human	PMID:19557502
Molecular Function	GO:0005515	protein binding	RIOK3	IPI	UniProtKB:Q92851	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	RIOK3	IPI	UniProtKB:Q14653	Human	PMID:24807708
Molecular Function	GO:0005515	protein binding	RIOK3	IPI	UniProtKB:Q9UHD2	Human	PMID:24807708
Molecular Function	GO:0005515	protein binding	RIOK3	IPI	UniProtKB:Q9BYX4	Human	PMID:25865883
Molecular Function	GO:0004674	protein serine/threonine kinase activity	RIOK3	IDA		Human	PMID:25865883
Cellular Component	GO:0030688	preribosome, small subunit precursor	RIOK3	IDA		Human	PMID:22072790
Cellular Component	GO:0030688	preribosome, small subunit precursor	RIOK3	IDA		Human	PMID:22418843
Biological Process	GO:1990786	cellular response to dsDNA	RIOK3	IMP		Human	PMID:24807708
Biological Process	GO:0071359	cellular response to dsRNA	RIOK3	IMP		Human	PMID:24807708
Biological Process	GO:0098586	cellular response to virus	RIOK3	IMP		Human	PMID:24807708
Biological Process	GO:0030490	maturation of SSU-rRNA	RIOK3	IMP		Human	PMID:22418843
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	RIOK3	IDA		Human	PMID:19557502
Biological Process	GO:0039534	negative regulation of MDA-5 signaling pathway	RIOK3	IMP		Human	PMID:25865883
Biological Process	GO:0031333	negative regulation of protein-containing complex assembly	RIOK3	IDA		Human	PMID:25865883
Biological Process	GO:0045089	positive regulation of innate immune response	RIOK3	IMP		Human	PMID:24807708
Biological Process	GO:0032728	positive regulation of interferon-beta production	RIOK3	IMP		Human	PMID:24807708

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern